Comprehensive analysis of a cuproptosis-related ceRNA network implicates a potential endocrine therapy resistance mechanism in ER-positive breast cancer

Comprehensive analysis of a cuproptosis-related ceRNA network implicates a potential endocrine therapy resistance mechanism in ER-positive breast cancer

Abstract Background While adjuvant endocrine therapy (ET) may decrease the mortality rate of estrogen receptor-positive (ER+) breast cancer (BC), the likelihood of relapse and metastasis due to ET resistance remains high. Cuproptosis is a recently discovered regulated cell death (RCD), whose role in...

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Bibliographic Details
Main Authors: Dongni Zhang, Wenping Lu, Zhili Zhuo, Yanan Wang, Weixuan Zhang, Mengfan Zhang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Medical Genomics
Subjects:
Breast cancer
ceRNA network
Endocrine therapy resistance
Cuproptosis
Prognosis
Online Access:https://doi.org/10.1186/s12920-023-01511-0

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