Cardiooncology. Basic principles of prevention and treatment of cardiotoxicity in cancer patients
Advances in the diagnostics and treatment of cancer have led to improved survival of patients and decreased mortality. Cardiovascular complications (CVC) however, are among the most frequent side effects of anticancer treatment, which can have an adverse effect on the prognosis. This may be the resu...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Eco-vector
2019-04-01
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| Series: | Клиническая практика |
| Subjects: | |
| Online Access: | https://journals.eco-vector.com/clinpractice/article/viewFile/10980/9284 |
| _version_ | 1827882196891860992 |
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| author | Ekaterina V. Plokhova David P. Doundoua |
| author_facet | Ekaterina V. Plokhova David P. Doundoua |
| author_sort | Ekaterina V. Plokhova |
| collection | DOAJ |
| description | Advances in the diagnostics and treatment of cancer have led to improved survival of patients and decreased mortality. Cardiovascular complications (CVC) however, are among the most frequent side effects of anticancer treatment, which can have an adverse effect on the prognosis. This may be the result of cardiotoxicity, which involves direct effects of the radiation therapy and /or chemotherapy on the heart function and structure. Heart failure with cancer therapy was associated with a 3.5-fold increase in the risk of mortality compared with idiopathic cardiomyopathy. The cardiotoxicity risk assessment is often difficult, due to the different susceptibility of patients to drugs and their combinations, and coadministration of radiation therapy. Therefore, the likelihood of development and the time of occurrence of cardiotoxicity may vary and not always depend on the initial risk. Strategies for managing such patients are in most cases based on the expert opinion. This article provides recommendations for the prevention and therapy of cardiotoxicity, set out in the consensus of the European Society of Cardiology 2016. |
| first_indexed | 2024-03-12T18:52:02Z |
| format | Article |
| id | doaj.art-dc56cd4b0755445fbaf7ab87b23a1370 |
| institution | Directory Open Access Journal |
| issn | 2220-3095 2618-8627 |
| language | English |
| last_indexed | 2024-03-12T18:52:02Z |
| publishDate | 2019-04-01 |
| publisher | Eco-vector |
| record_format | Article |
| series | Клиническая практика |
| spelling | doaj.art-dc56cd4b0755445fbaf7ab87b23a13702023-08-02T07:12:41ZengEco-vectorКлиническая практика2220-30952618-86272019-04-01101304010.17816/clinpract10130-4010066Cardiooncology. Basic principles of prevention and treatment of cardiotoxicity in cancer patientsEkaterina V. Plokhova0David P. Doundoua1Federal Research and Clinical Center FMBAFederal Research and Clinical Center FMBAAdvances in the diagnostics and treatment of cancer have led to improved survival of patients and decreased mortality. Cardiovascular complications (CVC) however, are among the most frequent side effects of anticancer treatment, which can have an adverse effect on the prognosis. This may be the result of cardiotoxicity, which involves direct effects of the radiation therapy and /or chemotherapy on the heart function and structure. Heart failure with cancer therapy was associated with a 3.5-fold increase in the risk of mortality compared with idiopathic cardiomyopathy. The cardiotoxicity risk assessment is often difficult, due to the different susceptibility of patients to drugs and their combinations, and coadministration of radiation therapy. Therefore, the likelihood of development and the time of occurrence of cardiotoxicity may vary and not always depend on the initial risk. Strategies for managing such patients are in most cases based on the expert opinion. This article provides recommendations for the prevention and therapy of cardiotoxicity, set out in the consensus of the European Society of Cardiology 2016.https://journals.eco-vector.com/clinpractice/article/viewFile/10980/9284cardiooncologycardiotoxicityleft ventricular dysfunctionheart failure |
| spellingShingle | Ekaterina V. Plokhova David P. Doundoua Cardiooncology. Basic principles of prevention and treatment of cardiotoxicity in cancer patients Клиническая практика cardiooncology cardiotoxicity left ventricular dysfunction heart failure |
| title | Cardiooncology. Basic principles of prevention and treatment of cardiotoxicity in cancer patients |
| title_full | Cardiooncology. Basic principles of prevention and treatment of cardiotoxicity in cancer patients |
| title_fullStr | Cardiooncology. Basic principles of prevention and treatment of cardiotoxicity in cancer patients |
| title_full_unstemmed | Cardiooncology. Basic principles of prevention and treatment of cardiotoxicity in cancer patients |
| title_short | Cardiooncology. Basic principles of prevention and treatment of cardiotoxicity in cancer patients |
| title_sort | cardiooncology basic principles of prevention and treatment of cardiotoxicity in cancer patients |
| topic | cardiooncology cardiotoxicity left ventricular dysfunction heart failure |
| url | https://journals.eco-vector.com/clinpractice/article/viewFile/10980/9284 |
| work_keys_str_mv | AT ekaterinavplokhova cardiooncologybasicprinciplesofpreventionandtreatmentofcardiotoxicityincancerpatients AT davidpdoundoua cardiooncologybasicprinciplesofpreventionandtreatmentofcardiotoxicityincancerpatients |