Possible Etiological Factors for the Development of Molar Incisor Hypomineralization (MIH) in Austrian Children

Background: Molar incisor hypomineralization (MIH) is a developmental enamel defect that primarily affects the first permanent molars and sometimes the incisors. Its increasing prevalence worldwide has raised clinical concerns, yet its exact cause remains unknown. This study aimed to assess potentia...

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Main Authors: Sarra Altner, Ivan Milutinovic, Katrin Bekes
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Dentistry Journal
Subjects:
Online Access:https://www.mdpi.com/2304-6767/12/3/44
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author Sarra Altner
Ivan Milutinovic
Katrin Bekes
author_facet Sarra Altner
Ivan Milutinovic
Katrin Bekes
author_sort Sarra Altner
collection DOAJ
description Background: Molar incisor hypomineralization (MIH) is a developmental enamel defect that primarily affects the first permanent molars and sometimes the incisors. Its increasing prevalence worldwide has raised clinical concerns, yet its exact cause remains unknown. This study aimed to assess potential factors influencing MIH development by analyzing the medical history of children aged 6 to 12 years using a questionnaire. Methods: This study included 100 children aged 6–12 years diagnosed with MIH during dental examination, and 100 age-matched children in the non-MIH (healthy) group from the Department of Pediatric Dentistry, University Clinic of Dentistry, Medical University of Vienna. The parents of the participants completed a two-page questionnaire regarding possible etiological factors of MIH. Results: The data analysis involved 100 children with MIH (mean age 8.5; ±1.3; 52% female) and 100 children in the healthy group (mean age 9.2; ±1.3; 42% female). The optimized binary logistic regression analysis revealed a significant association between MIH development and cesarean-section delivery (OR = 3; CI = [1.5–6.2]) and sixth disease (roseola) (OR = 3.5; CI = [1.5–8.0]). Conclusions: This study suggests that cesarean-section delivery and sixth disease (roseola) might increase the likelihood of MIH development in children.
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spelling doaj.art-dc573d065a67420fb849ee78e644067f2024-03-27T13:32:58ZengMDPI AGDentistry Journal2304-67672024-02-011234410.3390/dj12030044Possible Etiological Factors for the Development of Molar Incisor Hypomineralization (MIH) in Austrian ChildrenSarra Altner0Ivan Milutinovic1Katrin Bekes2Department of Paediatric Dentistry, School of Dentistry, Medical University of Vienna, Sensengasse 2a, 1090 Vienna, AustriaDepartment of Paediatric Dentistry, School of Dentistry, Medical University of Vienna, Sensengasse 2a, 1090 Vienna, AustriaDepartment of Paediatric Dentistry, School of Dentistry, Medical University of Vienna, Sensengasse 2a, 1090 Vienna, AustriaBackground: Molar incisor hypomineralization (MIH) is a developmental enamel defect that primarily affects the first permanent molars and sometimes the incisors. Its increasing prevalence worldwide has raised clinical concerns, yet its exact cause remains unknown. This study aimed to assess potential factors influencing MIH development by analyzing the medical history of children aged 6 to 12 years using a questionnaire. Methods: This study included 100 children aged 6–12 years diagnosed with MIH during dental examination, and 100 age-matched children in the non-MIH (healthy) group from the Department of Pediatric Dentistry, University Clinic of Dentistry, Medical University of Vienna. The parents of the participants completed a two-page questionnaire regarding possible etiological factors of MIH. Results: The data analysis involved 100 children with MIH (mean age 8.5; ±1.3; 52% female) and 100 children in the healthy group (mean age 9.2; ±1.3; 42% female). The optimized binary logistic regression analysis revealed a significant association between MIH development and cesarean-section delivery (OR = 3; CI = [1.5–6.2]) and sixth disease (roseola) (OR = 3.5; CI = [1.5–8.0]). Conclusions: This study suggests that cesarean-section delivery and sixth disease (roseola) might increase the likelihood of MIH development in children.https://www.mdpi.com/2304-6767/12/3/44molar incisor hypomineralizationetiologystructural anomalypediatric dentistry
spellingShingle Sarra Altner
Ivan Milutinovic
Katrin Bekes
Possible Etiological Factors for the Development of Molar Incisor Hypomineralization (MIH) in Austrian Children
Dentistry Journal
molar incisor hypomineralization
etiology
structural anomaly
pediatric dentistry
title Possible Etiological Factors for the Development of Molar Incisor Hypomineralization (MIH) in Austrian Children
title_full Possible Etiological Factors for the Development of Molar Incisor Hypomineralization (MIH) in Austrian Children
title_fullStr Possible Etiological Factors for the Development of Molar Incisor Hypomineralization (MIH) in Austrian Children
title_full_unstemmed Possible Etiological Factors for the Development of Molar Incisor Hypomineralization (MIH) in Austrian Children
title_short Possible Etiological Factors for the Development of Molar Incisor Hypomineralization (MIH) in Austrian Children
title_sort possible etiological factors for the development of molar incisor hypomineralization mih in austrian children
topic molar incisor hypomineralization
etiology
structural anomaly
pediatric dentistry
url https://www.mdpi.com/2304-6767/12/3/44
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AT katrinbekes possibleetiologicalfactorsforthedevelopmentofmolarincisorhypomineralizationmihinaustrianchildren