Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, Colombia
In 2014, vaccinia virus (VACV) infections were identified among farmworkers in Caquetá Department, Colombia; additional cases were identified in Cundinamarca Department in 2015. VACV, an orthopoxvirus (OPXV) used in the smallpox vaccine, has caused sporadic bovine and human outbreaks in countries su...
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2019-12-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/25/12/18-1114_article |
| _version_ | 1819147791419572224 |
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| author | Ashley Styczynski Jillybeth Burgado Diana Walteros José Usme-Ciro Katherine Laiton Alejandra Pinilla Farias Yoshinori Nakazawa Christina Chapman Whitni Davidson Matthew Mauldin Clint Morgan Juan Martínez-Cerón Edilson Patiña Leidy Laura López Sepúlveda Claudia Patricia Torres Anyely Eliana Cruz Suarez Gina Paez Olaya Carlos Elkin Riveros Diana Yaneth Cepeda Leydi Acosta Lopez Daniela Gomez Espinosa Faiber Antonio Gutierrez Lozada Yu Li P.S. Satheshkumar Mary Reynolds Martha Gracia-Romero Brett Petersen |
| author_facet | Ashley Styczynski Jillybeth Burgado Diana Walteros José Usme-Ciro Katherine Laiton Alejandra Pinilla Farias Yoshinori Nakazawa Christina Chapman Whitni Davidson Matthew Mauldin Clint Morgan Juan Martínez-Cerón Edilson Patiña Leidy Laura López Sepúlveda Claudia Patricia Torres Anyely Eliana Cruz Suarez Gina Paez Olaya Carlos Elkin Riveros Diana Yaneth Cepeda Leydi Acosta Lopez Daniela Gomez Espinosa Faiber Antonio Gutierrez Lozada Yu Li P.S. Satheshkumar Mary Reynolds Martha Gracia-Romero Brett Petersen |
| author_sort | Ashley Styczynski |
| collection | DOAJ |
| description | In 2014, vaccinia virus (VACV) infections were identified among farmworkers in Caquetá Department, Colombia; additional cases were identified in Cundinamarca Department in 2015. VACV, an orthopoxvirus (OPXV) used in the smallpox vaccine, has caused sporadic bovine and human outbreaks in countries such as Brazil and India. In response to the emergence of this disease in Colombia, we surveyed and collected blood from 134 farmworkers and household members from 56 farms in Cundinamarca Department. We tested serum samples for OPXV antibodies and correlated risk factors with seropositivity by using multivariate analyses. Fifty-two percent of farmworkers had OPXV antibodies; this percentage decreased to 31% when we excluded persons who would have been eligible for smallpox vaccination. The major risk factors for seropositivity were municipality, age, smallpox vaccination scar, duration of time working on a farm, and animals having vaccinia-like lesions. This investigation provides evidence for possible emergence of VACV as a zoonosis in South America. |
| first_indexed | 2024-12-22T13:35:26Z |
| format | Article |
| id | doaj.art-dc573f3a5ca24f14a9bbe06944cc8dc2 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-22T13:35:26Z |
| publishDate | 2019-12-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-dc573f3a5ca24f14a9bbe06944cc8dc22022-12-21T18:24:04ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592019-12-0125122169217610.3201/eid2512.181114Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, ColombiaAshley StyczynskiJillybeth BurgadoDiana WalterosJosé Usme-CiroKatherine LaitonAlejandra Pinilla FariasYoshinori NakazawaChristina ChapmanWhitni DavidsonMatthew MauldinClint MorganJuan Martínez-CerónEdilson PatiñaLeidy Laura López SepúlvedaClaudia Patricia TorresAnyely Eliana Cruz SuarezGina Paez OlayaCarlos Elkin RiverosDiana Yaneth CepedaLeydi Acosta LopezDaniela Gomez EspinosaFaiber Antonio Gutierrez LozadaYu LiP.S. SatheshkumarMary ReynoldsMartha Gracia-RomeroBrett PetersenIn 2014, vaccinia virus (VACV) infections were identified among farmworkers in Caquetá Department, Colombia; additional cases were identified in Cundinamarca Department in 2015. VACV, an orthopoxvirus (OPXV) used in the smallpox vaccine, has caused sporadic bovine and human outbreaks in countries such as Brazil and India. In response to the emergence of this disease in Colombia, we surveyed and collected blood from 134 farmworkers and household members from 56 farms in Cundinamarca Department. We tested serum samples for OPXV antibodies and correlated risk factors with seropositivity by using multivariate analyses. Fifty-two percent of farmworkers had OPXV antibodies; this percentage decreased to 31% when we excluded persons who would have been eligible for smallpox vaccination. The major risk factors for seropositivity were municipality, age, smallpox vaccination scar, duration of time working on a farm, and animals having vaccinia-like lesions. This investigation provides evidence for possible emergence of VACV as a zoonosis in South America.https://wwwnc.cdc.gov/eid/article/25/12/18-1114_articlevaccinia virusorthopox viruszoonoticdairy farmsColombiaviruses |
| spellingShingle | Ashley Styczynski Jillybeth Burgado Diana Walteros José Usme-Ciro Katherine Laiton Alejandra Pinilla Farias Yoshinori Nakazawa Christina Chapman Whitni Davidson Matthew Mauldin Clint Morgan Juan Martínez-Cerón Edilson Patiña Leidy Laura López Sepúlveda Claudia Patricia Torres Anyely Eliana Cruz Suarez Gina Paez Olaya Carlos Elkin Riveros Diana Yaneth Cepeda Leydi Acosta Lopez Daniela Gomez Espinosa Faiber Antonio Gutierrez Lozada Yu Li P.S. Satheshkumar Mary Reynolds Martha Gracia-Romero Brett Petersen Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, Colombia Emerging Infectious Diseases vaccinia virus orthopox virus zoonotic dairy farms Colombia viruses |
| title | Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, Colombia |
| title_full | Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, Colombia |
| title_fullStr | Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, Colombia |
| title_full_unstemmed | Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, Colombia |
| title_short | Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, Colombia |
| title_sort | seroprevalence and risk factors possibly associated with emerging zoonotic vaccinia virus in a farming community colombia |
| topic | vaccinia virus orthopox virus zoonotic dairy farms Colombia viruses |
| url | https://wwwnc.cdc.gov/eid/article/25/12/18-1114_article |
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