Noise-induced network bursts and coherence in a calcium-mediated neural network
Noise-induced population bursting has been widely identified to play important roles in information processes. We construct a mathematical model for a random and sparse heterogeneous neural network where bursting can be induced from a resting state by a global stochastic stimulus. Importantly, the n...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844021027158 |
| _version_ | 1828147717711331328 |
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| author | Na Yu Gurpreet Jagdev Michelle Morgovsky |
| author_facet | Na Yu Gurpreet Jagdev Michelle Morgovsky |
| author_sort | Na Yu |
| collection | DOAJ |
| description | Noise-induced population bursting has been widely identified to play important roles in information processes. We construct a mathematical model for a random and sparse heterogeneous neural network where bursting can be induced from a resting state by a global stochastic stimulus. Importantly, the noise-induced bursting dynamics of this network are mediated by calcium conductance. We use two spectral measures to evaluate network coherence in the context of the network bursts, the spike trains of all neurons, and the individual bursts of all neurons. Our results show that the coherence of the network is optimized by an optimal level of the stochastic stimulus, which is known as coherence resonance (CR). We also demonstrate that the interplay of the calcium conductance and noise intensity can modify the degree of CR. |
| first_indexed | 2024-04-11T21:04:14Z |
| format | Article |
| id | doaj.art-dc59b4cc99f94aa3ae8867770c507b8f |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-11T21:04:14Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-dc59b4cc99f94aa3ae8867770c507b8f2022-12-22T04:03:24ZengElsevierHeliyon2405-84402021-12-01712e08612Noise-induced network bursts and coherence in a calcium-mediated neural networkNa Yu0Gurpreet Jagdev1Michelle Morgovsky2Department of Mathematics, Ryerson University, Toronto, Canada; Corresponding author.Department of Mathematics, Ryerson University, Toronto, CanadaDepartment of Chemistry and Biology, Ryerson University, Toronto, CanadaNoise-induced population bursting has been widely identified to play important roles in information processes. We construct a mathematical model for a random and sparse heterogeneous neural network where bursting can be induced from a resting state by a global stochastic stimulus. Importantly, the noise-induced bursting dynamics of this network are mediated by calcium conductance. We use two spectral measures to evaluate network coherence in the context of the network bursts, the spike trains of all neurons, and the individual bursts of all neurons. Our results show that the coherence of the network is optimized by an optimal level of the stochastic stimulus, which is known as coherence resonance (CR). We also demonstrate that the interplay of the calcium conductance and noise intensity can modify the degree of CR.http://www.sciencedirect.com/science/article/pii/S2405844021027158Noise-induced burst firingPopulation burstsCoherence resonanceHeterogeneous network |
| spellingShingle | Na Yu Gurpreet Jagdev Michelle Morgovsky Noise-induced network bursts and coherence in a calcium-mediated neural network Heliyon Noise-induced burst firing Population bursts Coherence resonance Heterogeneous network |
| title | Noise-induced network bursts and coherence in a calcium-mediated neural network |
| title_full | Noise-induced network bursts and coherence in a calcium-mediated neural network |
| title_fullStr | Noise-induced network bursts and coherence in a calcium-mediated neural network |
| title_full_unstemmed | Noise-induced network bursts and coherence in a calcium-mediated neural network |
| title_short | Noise-induced network bursts and coherence in a calcium-mediated neural network |
| title_sort | noise induced network bursts and coherence in a calcium mediated neural network |
| topic | Noise-induced burst firing Population bursts Coherence resonance Heterogeneous network |
| url | http://www.sciencedirect.com/science/article/pii/S2405844021027158 |
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