Epigenetic Regulators of DNA Cytosine Modification: Promising Targets for Cancer Therapy

Epigenetic Regulators of DNA Cytosine Modification: Promising Targets for Cancer Therapy

Epigenetic modifications are crucial regulators of gene expression that critically impact cell lineage differentiation, survival, and proliferation, and dysregulations are commonly observed in various cancers. The aberrantly modified epigenome confers unique features on tumor cells, including sustai...

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Bibliographic Details
Main Authors: Inkyung Jung, Jungeun An, Myunggon Ko
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
epigenetics
DNMT
TET dioxygenases
DNA methylation and demethylation
small molecules
cancer therapy
Online Access:https://www.mdpi.com/2227-9059/11/3/654

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