The emerging therapeutic role of some pharmacological antidotes in management of COVID-19
Abstract Background A novel RNA coronavirus was identified in January 2020 as the cause of a pneumonia epidemic affecting the city of Wuhan; it rapidly spread across China. Aim of the review The aim is to discuss the potential efficacy of some pharmacologically known pharmacological antidotes (N-ace...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-01-01
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| Series: | The Egyptian Journal of Bronchology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43168-021-00105-7 |
| _version_ | 1819261214723670016 |
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| author | Doaa M. El Shehaby Marwa Kh. Mohammed Noha Esmael Ebrahem Mariam M. Abd El-Azim Islam G. Sayed Sarah A. Eweda |
| author_facet | Doaa M. El Shehaby Marwa Kh. Mohammed Noha Esmael Ebrahem Mariam M. Abd El-Azim Islam G. Sayed Sarah A. Eweda |
| author_sort | Doaa M. El Shehaby |
| collection | DOAJ |
| description | Abstract Background A novel RNA coronavirus was identified in January 2020 as the cause of a pneumonia epidemic affecting the city of Wuhan; it rapidly spread across China. Aim of the review The aim is to discuss the potential efficacy of some pharmacologically known pharmacological antidotes (N-acetylcysteine; hyperbaric oxygen; deferoxamine; low-dose naloxone) for the management of COVID-19-associated symptoms and complications. Method An extensive search was accomplished in Medline, Embase, Scopus, Web of Science, and Central databases until the end of April, 2021. Four independent researchers completed the screening, and finally, the associated studies were involved. Conclusion The current proof hinders the experts for suggesting the proper pharmacological lines of treatment of COVID-19. Organizations, for example, WHO, should pursue more practical actions and design well-planned clinical trials so that their results may be used in the treatment of future outbreaks. |
| first_indexed | 2024-12-23T19:38:15Z |
| format | Article |
| id | doaj.art-dc5a7a8c1c864e4fa15f3b9b4d242eb7 |
| institution | Directory Open Access Journal |
| issn | 1687-8426 2314-8551 |
| language | English |
| last_indexed | 2024-12-23T19:38:15Z |
| publishDate | 2022-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Bronchology |
| spelling | doaj.art-dc5a7a8c1c864e4fa15f3b9b4d242eb72022-12-21T17:33:45ZengSpringerOpenThe Egyptian Journal of Bronchology1687-84262314-85512022-01-0116111210.1186/s43168-021-00105-7The emerging therapeutic role of some pharmacological antidotes in management of COVID-19Doaa M. El Shehaby0Marwa Kh. Mohammed1Noha Esmael Ebrahem2Mariam M. Abd El-Azim3Islam G. Sayed4Sarah A. Eweda5Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Assiut UniversityForensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Assiut UniversityForensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Assiut UniversityForensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Assiut UniversityChest Department, Faculty of Medicine, Aswan UniversityForensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Ain Shams UniversityAbstract Background A novel RNA coronavirus was identified in January 2020 as the cause of a pneumonia epidemic affecting the city of Wuhan; it rapidly spread across China. Aim of the review The aim is to discuss the potential efficacy of some pharmacologically known pharmacological antidotes (N-acetylcysteine; hyperbaric oxygen; deferoxamine; low-dose naloxone) for the management of COVID-19-associated symptoms and complications. Method An extensive search was accomplished in Medline, Embase, Scopus, Web of Science, and Central databases until the end of April, 2021. Four independent researchers completed the screening, and finally, the associated studies were involved. Conclusion The current proof hinders the experts for suggesting the proper pharmacological lines of treatment of COVID-19. Organizations, for example, WHO, should pursue more practical actions and design well-planned clinical trials so that their results may be used in the treatment of future outbreaks.https://doi.org/10.1186/s43168-021-00105-7COVID-19NACHBODeferoxamineLDN |
| spellingShingle | Doaa M. El Shehaby Marwa Kh. Mohammed Noha Esmael Ebrahem Mariam M. Abd El-Azim Islam G. Sayed Sarah A. Eweda The emerging therapeutic role of some pharmacological antidotes in management of COVID-19 The Egyptian Journal of Bronchology COVID-19 NAC HBO Deferoxamine LDN |
| title | The emerging therapeutic role of some pharmacological antidotes in management of COVID-19 |
| title_full | The emerging therapeutic role of some pharmacological antidotes in management of COVID-19 |
| title_fullStr | The emerging therapeutic role of some pharmacological antidotes in management of COVID-19 |
| title_full_unstemmed | The emerging therapeutic role of some pharmacological antidotes in management of COVID-19 |
| title_short | The emerging therapeutic role of some pharmacological antidotes in management of COVID-19 |
| title_sort | emerging therapeutic role of some pharmacological antidotes in management of covid 19 |
| topic | COVID-19 NAC HBO Deferoxamine LDN |
| url | https://doi.org/10.1186/s43168-021-00105-7 |
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