The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients
In COVID-19 the development of severe viral pneumonia that is coupled with systemic inflammatory response triggers multi-organ failure and is of major concern. Cardiac involvement occurs in nearly 60% of patients with pre-existing cardiovascular conditions and heralds worse clinical outcome. Diagnos...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.854750/full |
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| author | Alessandra Borlotti Helena Thomaides-Brears Georgios Georgiopoulos Georgios Georgiopoulos Rajarshi Banerjee Matthew D. Robson Dahlene N. Fusco Pier-Giorgio Masci Pier-Giorgio Masci |
| author_facet | Alessandra Borlotti Helena Thomaides-Brears Georgios Georgiopoulos Georgios Georgiopoulos Rajarshi Banerjee Matthew D. Robson Dahlene N. Fusco Pier-Giorgio Masci Pier-Giorgio Masci |
| author_sort | Alessandra Borlotti |
| collection | DOAJ |
| description | In COVID-19 the development of severe viral pneumonia that is coupled with systemic inflammatory response triggers multi-organ failure and is of major concern. Cardiac involvement occurs in nearly 60% of patients with pre-existing cardiovascular conditions and heralds worse clinical outcome. Diagnoses carried out in the acute phase of COVID-19 rely upon increased levels of circulating cardiac injury biomarkers and transthoracic echocardiography. These diagnostics, however, were unable to pinpoint the mechanisms of cardiac injury in COVID-19 patients. Identifying the main features of cardiac injury remains an urgent yet unmet need in cardiology, given the potential clinical consequences. Cardiovascular magnetic resonance (CMR) provides an unparalleled opportunity to gain a deeper insight into myocardial injury given its unique ability to interrogate the properties of myocardial tissue. This endeavor is particularly important in convalescent COVID-19 patients as many continue to experience chest pain, palpitations, dyspnea and exertional fatigue, six or more months after the acute illness. This review will provide a critical appraisal of research on cardiovascular damage in convalescent adult COVID-19 patients with an emphasis on the use of CMR and its value to our understanding of organ damage. |
| first_indexed | 2024-12-14T06:01:39Z |
| format | Article |
| id | doaj.art-dc5e915db6d2404d87d7a82ae0e0f924 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-12-14T06:01:39Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-dc5e915db6d2404d87d7a82ae0e0f9242022-12-21T23:14:26ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-04-01910.3389/fcvm.2022.854750854750The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 PatientsAlessandra Borlotti0Helena Thomaides-Brears1Georgios Georgiopoulos2Georgios Georgiopoulos3Rajarshi Banerjee4Matthew D. Robson5Dahlene N. Fusco6Pier-Giorgio Masci7Pier-Giorgio Masci8Perspectum Ltd., Oxford, United KingdomPerspectum Ltd., Oxford, United KingdomSchool of Biomedical Engineering and Imaging Sciences, King’s College London, London, United KingdomDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, GreecePerspectum Ltd., Oxford, United KingdomPerspectum Ltd., Oxford, United KingdomTulane University School of Medicine, New Orleans, LA, United StatesPerspectum Ltd., Oxford, United KingdomSchool of Biomedical Engineering and Imaging Sciences, King’s College London, London, United KingdomIn COVID-19 the development of severe viral pneumonia that is coupled with systemic inflammatory response triggers multi-organ failure and is of major concern. Cardiac involvement occurs in nearly 60% of patients with pre-existing cardiovascular conditions and heralds worse clinical outcome. Diagnoses carried out in the acute phase of COVID-19 rely upon increased levels of circulating cardiac injury biomarkers and transthoracic echocardiography. These diagnostics, however, were unable to pinpoint the mechanisms of cardiac injury in COVID-19 patients. Identifying the main features of cardiac injury remains an urgent yet unmet need in cardiology, given the potential clinical consequences. Cardiovascular magnetic resonance (CMR) provides an unparalleled opportunity to gain a deeper insight into myocardial injury given its unique ability to interrogate the properties of myocardial tissue. This endeavor is particularly important in convalescent COVID-19 patients as many continue to experience chest pain, palpitations, dyspnea and exertional fatigue, six or more months after the acute illness. This review will provide a critical appraisal of research on cardiovascular damage in convalescent adult COVID-19 patients with an emphasis on the use of CMR and its value to our understanding of organ damage.https://www.frontiersin.org/articles/10.3389/fcvm.2022.854750/fullcardiovascular magnetic resonanacelong-COVIDmyocardial injurymulti-organ damageconvalescent COVID-19 patients |
| spellingShingle | Alessandra Borlotti Helena Thomaides-Brears Georgios Georgiopoulos Georgios Georgiopoulos Rajarshi Banerjee Matthew D. Robson Dahlene N. Fusco Pier-Giorgio Masci Pier-Giorgio Masci The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients Frontiers in Cardiovascular Medicine cardiovascular magnetic resonanace long-COVID myocardial injury multi-organ damage convalescent COVID-19 patients |
| title | The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients |
| title_full | The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients |
| title_fullStr | The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients |
| title_full_unstemmed | The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients |
| title_short | The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients |
| title_sort | additive value of cardiovascular magnetic resonance in convalescent covid 19 patients |
| topic | cardiovascular magnetic resonanace long-COVID myocardial injury multi-organ damage convalescent COVID-19 patients |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.854750/full |
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