Nanomaterials-incorporated hydrogels for 3D bioprinting technology
Abstract In the field of tissue engineering and regenerative medicine, various hydrogels derived from the extracellular matrix have been utilized for creating engineered tissues and implantable scaffolds. While these hydrogels hold immense promise in the healthcare landscape, conventional bioinks ba...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2023-11-01
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| Series: | Nano Convergence |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40580-023-00402-5 |
| _version_ | 1797557338626850816 |
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| author | Jungbin Yoon Hohyeon Han Jinah Jang |
| author_facet | Jungbin Yoon Hohyeon Han Jinah Jang |
| author_sort | Jungbin Yoon |
| collection | DOAJ |
| description | Abstract In the field of tissue engineering and regenerative medicine, various hydrogels derived from the extracellular matrix have been utilized for creating engineered tissues and implantable scaffolds. While these hydrogels hold immense promise in the healthcare landscape, conventional bioinks based on ECM hydrogels face several challenges, particularly in terms of lacking the necessary mechanical properties required for 3D bioprinting process. To address these limitations, researchers are actively exploring novel nanomaterial-reinforced ECM hydrogels for both mechanical and functional aspects. In this review, we focused on discussing recent advancements in the fabrication of engineered tissues and monitoring systems using nanobioinks and nanomaterials via 3D bioprinting technology. We highlighted the synergistic benefits of combining numerous nanomaterials into ECM hydrogels and imposing geometrical effects by 3D bioprinting technology. Furthermore, we also elaborated on critical issues remaining at the moment, such as the inhomogeneous dispersion of nanomaterials and consequent technical and practical issues, in the fabrication of complex 3D structures with nanobioinks and nanomaterials. Finally, we elaborated on plausible outlooks for facilitating the use of nanomaterials in biofabrication and advancing the function of engineered tissues. |
| first_indexed | 2024-03-10T17:15:45Z |
| format | Article |
| id | doaj.art-dc609605b005448298fde42f01d8cd29 |
| institution | Directory Open Access Journal |
| issn | 2196-5404 |
| language | English |
| last_indexed | 2024-03-10T17:15:45Z |
| publishDate | 2023-11-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Nano Convergence |
| spelling | doaj.art-dc609605b005448298fde42f01d8cd292023-11-20T10:31:51ZengSpringerOpenNano Convergence2196-54042023-11-0110112710.1186/s40580-023-00402-5Nanomaterials-incorporated hydrogels for 3D bioprinting technologyJungbin Yoon0Hohyeon Han1Jinah Jang2Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH)School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology (POSTECH)Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH)Abstract In the field of tissue engineering and regenerative medicine, various hydrogels derived from the extracellular matrix have been utilized for creating engineered tissues and implantable scaffolds. While these hydrogels hold immense promise in the healthcare landscape, conventional bioinks based on ECM hydrogels face several challenges, particularly in terms of lacking the necessary mechanical properties required for 3D bioprinting process. To address these limitations, researchers are actively exploring novel nanomaterial-reinforced ECM hydrogels for both mechanical and functional aspects. In this review, we focused on discussing recent advancements in the fabrication of engineered tissues and monitoring systems using nanobioinks and nanomaterials via 3D bioprinting technology. We highlighted the synergistic benefits of combining numerous nanomaterials into ECM hydrogels and imposing geometrical effects by 3D bioprinting technology. Furthermore, we also elaborated on critical issues remaining at the moment, such as the inhomogeneous dispersion of nanomaterials and consequent technical and practical issues, in the fabrication of complex 3D structures with nanobioinks and nanomaterials. Finally, we elaborated on plausible outlooks for facilitating the use of nanomaterials in biofabrication and advancing the function of engineered tissues.https://doi.org/10.1186/s40580-023-00402-5NanomaterialsNatural ECM hydrogel3D bioprintingEngineered tissue |
| spellingShingle | Jungbin Yoon Hohyeon Han Jinah Jang Nanomaterials-incorporated hydrogels for 3D bioprinting technology Nano Convergence Nanomaterials Natural ECM hydrogel 3D bioprinting Engineered tissue |
| title | Nanomaterials-incorporated hydrogels for 3D bioprinting technology |
| title_full | Nanomaterials-incorporated hydrogels for 3D bioprinting technology |
| title_fullStr | Nanomaterials-incorporated hydrogels for 3D bioprinting technology |
| title_full_unstemmed | Nanomaterials-incorporated hydrogels for 3D bioprinting technology |
| title_short | Nanomaterials-incorporated hydrogels for 3D bioprinting technology |
| title_sort | nanomaterials incorporated hydrogels for 3d bioprinting technology |
| topic | Nanomaterials Natural ECM hydrogel 3D bioprinting Engineered tissue |
| url | https://doi.org/10.1186/s40580-023-00402-5 |
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