Autologous Platelet-Rich Plasma (PRP) for Treating Androgenetic Alopecia: A Novel Treatment Protocol Standardized on 2 Cases

Platelet-rich plasma (PRP) treatment has emerged in recent years as a valuable, effective, and affordable treatment for androgenetic alopecia. Androgenetic alopecia is the most common type of alopecia, affecting both men and women, and is characterized by diminished hair follicles mainly pronounced...

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Main Authors: Ana Maletic, Ivo Dumic-Cule, Petar Brlek, Rado Zic, Dragan Primorac
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/24/7327
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author Ana Maletic
Ivo Dumic-Cule
Petar Brlek
Rado Zic
Dragan Primorac
author_facet Ana Maletic
Ivo Dumic-Cule
Petar Brlek
Rado Zic
Dragan Primorac
author_sort Ana Maletic
collection DOAJ
description Platelet-rich plasma (PRP) treatment has emerged in recent years as a valuable, effective, and affordable treatment for androgenetic alopecia. Androgenetic alopecia is the most common type of alopecia, affecting both men and women, and is characterized by diminished hair follicles mainly pronounced in the frontal region and vertex. A considerable variety of PRP treatment regimens have been described so far, but there is no consensus on the standardization of PRP preparation or administration protocol. Our study was conducted on two patients to test the efficacy of a new PRP application protocol of only two treatments by using a combination of a PRP collecting device and a conventional kit. Efficacy of treatment was assessed after a 6-month follow-up by artificial intelligence (AI)-driven software on microscopic images of treated regions. An average number of hairs, cumulative hair thickness, and the number of follicular units increased in the vertex region of both patients by 30/59%, 35/53%, and 14/48%, respectively. The novel treatment regimen showed significant effectiveness in only six months.
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spelling doaj.art-dc63786ce10a4c38814e836e08877c612023-11-24T15:43:39ZengMDPI AGJournal of Clinical Medicine2077-03832022-12-011124732710.3390/jcm11247327Autologous Platelet-Rich Plasma (PRP) for Treating Androgenetic Alopecia: A Novel Treatment Protocol Standardized on 2 CasesAna Maletic0Ivo Dumic-Cule1Petar Brlek2Rado Zic3Dragan Primorac4Polyclinic Maletic, 43500 Daruvar, CroatiaUniversity North, 42000 Varaždin, CroatiaSt. Catharine Special Hospital, 10000 Zagreb, CroatiaDepartment of Plastic Surgery, University Hospital Dubrava, 10040 Zagreb, CroatiaSt. Catharine Special Hospital, 10000 Zagreb, CroatiaPlatelet-rich plasma (PRP) treatment has emerged in recent years as a valuable, effective, and affordable treatment for androgenetic alopecia. Androgenetic alopecia is the most common type of alopecia, affecting both men and women, and is characterized by diminished hair follicles mainly pronounced in the frontal region and vertex. A considerable variety of PRP treatment regimens have been described so far, but there is no consensus on the standardization of PRP preparation or administration protocol. Our study was conducted on two patients to test the efficacy of a new PRP application protocol of only two treatments by using a combination of a PRP collecting device and a conventional kit. Efficacy of treatment was assessed after a 6-month follow-up by artificial intelligence (AI)-driven software on microscopic images of treated regions. An average number of hairs, cumulative hair thickness, and the number of follicular units increased in the vertex region of both patients by 30/59%, 35/53%, and 14/48%, respectively. The novel treatment regimen showed significant effectiveness in only six months.https://www.mdpi.com/2077-0383/11/24/7327androgenetic alopeciaplatelet-rich plasmahair losshair follicle
spellingShingle Ana Maletic
Ivo Dumic-Cule
Petar Brlek
Rado Zic
Dragan Primorac
Autologous Platelet-Rich Plasma (PRP) for Treating Androgenetic Alopecia: A Novel Treatment Protocol Standardized on 2 Cases
Journal of Clinical Medicine
androgenetic alopecia
platelet-rich plasma
hair loss
hair follicle
title Autologous Platelet-Rich Plasma (PRP) for Treating Androgenetic Alopecia: A Novel Treatment Protocol Standardized on 2 Cases
title_full Autologous Platelet-Rich Plasma (PRP) for Treating Androgenetic Alopecia: A Novel Treatment Protocol Standardized on 2 Cases
title_fullStr Autologous Platelet-Rich Plasma (PRP) for Treating Androgenetic Alopecia: A Novel Treatment Protocol Standardized on 2 Cases
title_full_unstemmed Autologous Platelet-Rich Plasma (PRP) for Treating Androgenetic Alopecia: A Novel Treatment Protocol Standardized on 2 Cases
title_short Autologous Platelet-Rich Plasma (PRP) for Treating Androgenetic Alopecia: A Novel Treatment Protocol Standardized on 2 Cases
title_sort autologous platelet rich plasma prp for treating androgenetic alopecia a novel treatment protocol standardized on 2 cases
topic androgenetic alopecia
platelet-rich plasma
hair loss
hair follicle
url https://www.mdpi.com/2077-0383/11/24/7327
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