Therapeutic Effect of Costunolide in Autoimmune Hepatitis: Network Pharmacology and Experimental Validation

Therapeutic Effect of Costunolide in Autoimmune Hepatitis: Network Pharmacology and Experimental Validation

Novel treatments for autoimmune hepatitis (AIH) are highly demanded due to the limitations of existing therapeutic agents. Costunolide is a promising candidate due to its anti-inflammatory and hepatoprotective function, but its effect in AIH remains obscure. In this study, we integrated network phar...

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Bibliographic Details
Main Authors:	Zheng Huang, Shangshu Nie, Shuhui Wang, Han Wang, Jin Gong, Wei Yan, Dean Tian, Mei Liu
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Series:	Pharmaceuticals
Subjects:	costunolide autoimmune hepatitis network pharmacology immune-mediated liver injury PI3K-AKT SRC
Online Access:	https://www.mdpi.com/1424-8247/16/2/316

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