Intestinal Flora Changes Induced by a High-Fat Diet Promote Activation of Primordial Follicles through Macrophage Infiltration and Inflammatory Factor Secretion in Mouse Ovaries

Intestinal Flora Changes Induced by a High-Fat Diet Promote Activation of Primordial Follicles through Macrophage Infiltration and Inflammatory Factor Secretion in Mouse Ovaries

Obesity induced by a high-fat diet (HFD) leads to the excessive consumption of primordial follicles (PFs) in the ovaries. There is systemic chronic inflammation under HFD conditions, but no previous studies have explored whether there is a certain causal relationship between HFD-induced chronic infl...

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Bibliographic Details
Main Authors: Zhihao Fan, Xiaoqian Zhang, Yanxing Shang, Maosheng Zou, Meng Zhou, Qiukai E, Shujia Fei, Wei Chen, Jing Li, Xuesen Zhang, Xiaoqiu Liu
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
high-fat diet
intestinal flora
primordial follicles
macrophages
STAT3
Online Access:https://www.mdpi.com/1422-0067/23/9/4797

Internet

https://www.mdpi.com/1422-0067/23/9/4797

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