p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes

p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes

Japanese encephalitis virus (JEV) targets central nervous system, resulting in neuroinflammation with typical features of neuronal death along with hyper activation of glial cells. Exploring the mechanisms responsible for the JEV-caused inflammatory response remains a pivotal area of research. In th...

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Bibliographic Details
Main Authors: Wen He, Zikai Zhao, Awais Anees, Yunchuan Li, Usama Ashraf, Zheng Chen, Yunfeng Song, Huanchun Chen, Shengbo Cao, Jing Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
JEV
PAK4
inflammation
MAPK
astrocyte
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00271/full

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