The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review

Abstract Over the past 30 years, the genus Solanum has received considerable attention in chemical and biological studies. Solanum is the largest genus in the family Solanaceae, comprising of about 2000 species distributed in the subtropical and tropical regions of Africa, Australia, and parts of As...

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Main Authors: Joseph Sakah Kaunda, Ying-Jun Zhang
Format: Article
Language:English
Published: SpringerOpen 2019-03-01
Series:Natural Products and Bioprospecting
Subjects:
Online Access:http://link.springer.com/article/10.1007/s13659-019-0201-6
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author Joseph Sakah Kaunda
Ying-Jun Zhang
author_facet Joseph Sakah Kaunda
Ying-Jun Zhang
author_sort Joseph Sakah Kaunda
collection DOAJ
description Abstract Over the past 30 years, the genus Solanum has received considerable attention in chemical and biological studies. Solanum is the largest genus in the family Solanaceae, comprising of about 2000 species distributed in the subtropical and tropical regions of Africa, Australia, and parts of Asia, e.g., China, India and Japan. Many of them are economically significant species. Previous phytochemical investigations on Solanum species led to the identification of steroidal saponins, steroidal alkaloids, terpenes, flavonoids, lignans, sterols, phenolic comopunds, coumarins, amongst other compounds. Many species belonging to this genus present huge range of pharmacological activities such as cytotoxicity to different tumors as breast cancer (4T1 and EMT), colorectal cancer (HCT116, HT29, and SW480), and prostate cancer (DU145) cell lines. The biological activities have been attributed to a number of steroidal saponins, steroidal alkaloids and phenols. This review features 65 phytochemically studied species of Solanum between 1990 and 2018, fetched from SciFinder, Pubmed, ScienceDirect, Wikipedia and Baidu, using “Solanum” and the species’ names as search terms (“all fields”).
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spelling doaj.art-dc6c7764de644c55969bf79f696c3f602022-12-22T01:55:35ZengSpringerOpenNatural Products and Bioprospecting2192-21952192-22092019-03-01927713710.1007/s13659-019-0201-6The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties ReviewJoseph Sakah Kaunda0Ying-Jun Zhang1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesAbstract Over the past 30 years, the genus Solanum has received considerable attention in chemical and biological studies. Solanum is the largest genus in the family Solanaceae, comprising of about 2000 species distributed in the subtropical and tropical regions of Africa, Australia, and parts of Asia, e.g., China, India and Japan. Many of them are economically significant species. Previous phytochemical investigations on Solanum species led to the identification of steroidal saponins, steroidal alkaloids, terpenes, flavonoids, lignans, sterols, phenolic comopunds, coumarins, amongst other compounds. Many species belonging to this genus present huge range of pharmacological activities such as cytotoxicity to different tumors as breast cancer (4T1 and EMT), colorectal cancer (HCT116, HT29, and SW480), and prostate cancer (DU145) cell lines. The biological activities have been attributed to a number of steroidal saponins, steroidal alkaloids and phenols. This review features 65 phytochemically studied species of Solanum between 1990 and 2018, fetched from SciFinder, Pubmed, ScienceDirect, Wikipedia and Baidu, using “Solanum” and the species’ names as search terms (“all fields”).http://link.springer.com/article/10.1007/s13659-019-0201-6SolanumSolanaceaePhytochemistrySteroidal saponins and alkaloidsEthnopharmacology
spellingShingle Joseph Sakah Kaunda
Ying-Jun Zhang
The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review
Natural Products and Bioprospecting
Solanum
Solanaceae
Phytochemistry
Steroidal saponins and alkaloids
Ethnopharmacology
title The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review
title_full The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review
title_fullStr The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review
title_full_unstemmed The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review
title_short The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review
title_sort genus solanum an ethnopharmacological phytochemical and biological properties review
topic Solanum
Solanaceae
Phytochemistry
Steroidal saponins and alkaloids
Ethnopharmacology
url http://link.springer.com/article/10.1007/s13659-019-0201-6
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