Emergence and Spread of Tetracycline resistant Vibrio cholerae O1 El Tor variant during 2010 cholera epidemic in the tribal areas of Odisha, India
Objectives: The epidemics of cholera were reported in the Kashipur, K.singhpur, B cuttack blocks of Rayagada district and Mohana block of Gajapati district of Odisha during 2010. The present study was carried out to isolate the bacterial pathogen, its drug sensitivity pattern and to describe the spr...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-04-01
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| Series: | International Journal of Infectious Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971214017433 |
| _version_ | 1818666293593636864 |
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| author | Santanu Kumar Kar Bibhuti Bhusan Pal Hemanta Kumar Khuntia K. Gopinath Achary Chinmaye Priyadarshini Khuntia |
| author_facet | Santanu Kumar Kar Bibhuti Bhusan Pal Hemanta Kumar Khuntia K. Gopinath Achary Chinmaye Priyadarshini Khuntia |
| author_sort | Santanu Kumar Kar |
| collection | DOAJ |
| description | Objectives: The epidemics of cholera were reported in the Kashipur, K.singhpur, B cuttack blocks of Rayagada district and Mohana block of Gajapati district of Odisha during 2010. The present study was carried out to isolate the bacterial pathogen, its drug sensitivity pattern and to describe the spread of the disease in those areas.
Methods: A total of 68 rectal swabs collected from patients with severe diarrhea, admitted to different health centers and diarrhea affected villages were bacteriologically analyzed. Similarly 22 water samples collected from different villages from nala, chua, etc were tested for the presence of V cholerae.
Results: Out of 68 rectal swabs tested 35 (51.5%) were V cholerae O1 Ogawa and 14(20.6%) were E coli; which might be commensals. All water samples were negative for V cholerae. The V cholerae strains were sensitive to gentamicin, norfloxacin, ciprofloxacin, azithromycin and ofloxacin; but were resistant to ampicillin, tetracycline, nalidixic acid, furazolidone, streptomycin, erythromycin, co-trimoxazole, neomycin and chloramphenicol. All V cholerae strains were 100% resistant to tetracycline and they were El Tor variants harboring ctxB gene of classical strain.
Conclusions: The present study indicated the emergence and spread of tetracycline resistant V cholerae O1 El Tor variant in the tribal areas which needs close monitoring. |
| first_indexed | 2024-12-17T06:02:14Z |
| format | Article |
| id | doaj.art-dc6c8b815d354cf899515dad09d73621 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 1878-3511 |
| language | English |
| last_indexed | 2024-12-17T06:02:14Z |
| publishDate | 2015-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-dc6c8b815d354cf899515dad09d736212022-12-21T22:00:50ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112015-04-0133C454910.1016/j.ijid.2014.12.025Emergence and Spread of Tetracycline resistant Vibrio cholerae O1 El Tor variant during 2010 cholera epidemic in the tribal areas of Odisha, IndiaSantanu Kumar KarBibhuti Bhusan PalHemanta Kumar KhuntiaK. Gopinath AcharyChinmaye Priyadarshini KhuntiaObjectives: The epidemics of cholera were reported in the Kashipur, K.singhpur, B cuttack blocks of Rayagada district and Mohana block of Gajapati district of Odisha during 2010. The present study was carried out to isolate the bacterial pathogen, its drug sensitivity pattern and to describe the spread of the disease in those areas. Methods: A total of 68 rectal swabs collected from patients with severe diarrhea, admitted to different health centers and diarrhea affected villages were bacteriologically analyzed. Similarly 22 water samples collected from different villages from nala, chua, etc were tested for the presence of V cholerae. Results: Out of 68 rectal swabs tested 35 (51.5%) were V cholerae O1 Ogawa and 14(20.6%) were E coli; which might be commensals. All water samples were negative for V cholerae. The V cholerae strains were sensitive to gentamicin, norfloxacin, ciprofloxacin, azithromycin and ofloxacin; but were resistant to ampicillin, tetracycline, nalidixic acid, furazolidone, streptomycin, erythromycin, co-trimoxazole, neomycin and chloramphenicol. All V cholerae strains were 100% resistant to tetracycline and they were El Tor variants harboring ctxB gene of classical strain. Conclusions: The present study indicated the emergence and spread of tetracycline resistant V cholerae O1 El Tor variant in the tribal areas which needs close monitoring.http://www.sciencedirect.com/science/article/pii/S1201971214017433El Tor variantV choleraespreadTetracycline resistance |
| spellingShingle | Santanu Kumar Kar Bibhuti Bhusan Pal Hemanta Kumar Khuntia K. Gopinath Achary Chinmaye Priyadarshini Khuntia Emergence and Spread of Tetracycline resistant Vibrio cholerae O1 El Tor variant during 2010 cholera epidemic in the tribal areas of Odisha, India International Journal of Infectious Diseases El Tor variant V cholerae spread Tetracycline resistance |
| title | Emergence and Spread of Tetracycline resistant Vibrio cholerae O1 El Tor variant during 2010 cholera epidemic in the tribal areas of Odisha, India |
| title_full | Emergence and Spread of Tetracycline resistant Vibrio cholerae O1 El Tor variant during 2010 cholera epidemic in the tribal areas of Odisha, India |
| title_fullStr | Emergence and Spread of Tetracycline resistant Vibrio cholerae O1 El Tor variant during 2010 cholera epidemic in the tribal areas of Odisha, India |
| title_full_unstemmed | Emergence and Spread of Tetracycline resistant Vibrio cholerae O1 El Tor variant during 2010 cholera epidemic in the tribal areas of Odisha, India |
| title_short | Emergence and Spread of Tetracycline resistant Vibrio cholerae O1 El Tor variant during 2010 cholera epidemic in the tribal areas of Odisha, India |
| title_sort | emergence and spread of tetracycline resistant vibrio cholerae o1 el tor variant during 2010 cholera epidemic in the tribal areas of odisha india |
| topic | El Tor variant V cholerae spread Tetracycline resistance |
| url | http://www.sciencedirect.com/science/article/pii/S1201971214017433 |
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