Miniaturized Bioaffinity Assessment Coupled to Mass Spectrometry for Guided Purification of Bioactives from Toad and Cone Snail

Miniaturized Bioaffinity Assessment Coupled to Mass Spectrometry for Guided Purification of Bioactives from Toad and Cone Snail

A nano-flow high-resolution screening platform, featuring a parallel chip-based microfluidic bioassay and mass spectrometry coupled to nano-liquid chromatography, was applied to screen animal venoms for nicotinic acetylcholine receptor like (nAChR) affinity by using the acetylcholine binding protein...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ferry Heus, Reka A. Otvos, Ruud L. E. G. Aspers, Rene van Elk, Jenny I. Halff, Andreas W. Ehlers, Sébastien Dutertre, Richard J. Lewis, Sybren Wijmenga, August B. Smit, Wilfried M. A. Niessen, Jeroen Kool
التنسيق: مقال
اللغة:English
منشور في: MDPI AG 2014-02-01
سلاسل:Biology
الموضوعات:
on-line microfluidics
nano-liquid chromatography-mass spectrometry (nano-LC-MS)
Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP)
Conus textile
Bufo alvarius
Bufo marinus
الوصول للمادة أونلاين:http://www.mdpi.com/2079-7737/3/1/139

الانترنت

http://www.mdpi.com/2079-7737/3/1/139

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