Miniaturized Bioaffinity Assessment Coupled to Mass Spectrometry for Guided Purification of Bioactives from Toad and Cone Snail
A nano-flow high-resolution screening platform, featuring a parallel chip-based microfluidic bioassay and mass spectrometry coupled to nano-liquid chromatography, was applied to screen animal venoms for nicotinic acetylcholine receptor like (nAChR) affinity by using the acetylcholine binding protein...
Hauptverfasser: | Ferry Heus, Reka A. Otvos, Ruud L. E. G. Aspers, Rene van Elk, Jenny I. Halff, Andreas W. Ehlers, Sébastien Dutertre, Richard J. Lewis, Sybren Wijmenga, August B. Smit, Wilfried M. A. Niessen, Jeroen Kool |
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Format: | Artikel |
Sprache: | English |
Veröffentlicht: |
MDPI AG
2014-02-01
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Schriftenreihe: | Biology |
Schlagworte: | |
Online Zugang: | http://www.mdpi.com/2079-7737/3/1/139 |
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