Bioinformatics Analysis Using ATAC-seq and RNA-seq for the Identification of 15 Gene Signatures Associated With the Prediction of Prognosis in Hepatocellular Carcinoma

Bioinformatics Analysis Using ATAC-seq and RNA-seq for the Identification of 15 Gene Signatures Associated With the Prediction of Prognosis in Hepatocellular Carcinoma

BackgroundGene expression (RNA-seq) and overall survival (OS) in TCGA were combined using chromosome accessibility (ATAC-seq) to search for key molecules affecting liver cancer prognosis.MethodsWe used the assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) to analy...

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Bibliographic Details
Main Authors: Hui Yang, Gang Li, Guangping Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
chromatin accessibility
ATAC-seq
hepatocellular liver cancer
LASSO model
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.726551/full

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