Natural vs Synthetic Polymers: How Do They Communicate with Cells for Skin Regeneration—A Review
Modern research has evolved several approaches toward skin regeneration and one of the novel concerns is the use of polymer-based systems due to their excellent beneficial properties to the skin. Several polymers, such as cellulose, hyaluronan, alginate, chitosan, collagen, fibrin and fibroin, have...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Journal of Composites Science |
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| Online Access: | https://www.mdpi.com/2504-477X/7/9/385 |
| _version_ | 1797579470822965248 |
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| author | Jeevithan Elango Camilo Zamora-Ledezma José Eduardo Maté-Sánchez de Val |
| author_facet | Jeevithan Elango Camilo Zamora-Ledezma José Eduardo Maté-Sánchez de Val |
| author_sort | Jeevithan Elango |
| collection | DOAJ |
| description | Modern research has evolved several approaches toward skin regeneration and one of the novel concerns is the use of polymer-based systems due to their excellent beneficial properties to the skin. Several polymers, such as cellulose, hyaluronan, alginate, chitosan, collagen, fibrin and fibroin, have been tested and have proven the benefits for skin regeneration, and most of them are derived from either polysaccharide- or protein-based materials. In order to understand the mode of action, several researchers investigated the cell–matrix interaction and possible signaling mechanism in skin regeneration. Not only the signaling mechanism but also the mode of cell communication determines the application of polysaccharide- and protein-based polymers in practice. Based on the above significance, this review disclosed the recent findings to compile a possible method of communication between cells and polymers derived from polysaccharide-based (such as cellulose, hyaluronan, chitosan, alginate, agar, and xanthan gum) and protein-based (such as collagen, gelatin, fibrin, and silk fibroin) materials along with other polymers, such as poly(vinyl alcohol), polyglycolide or poly(glycolic acid), or poly(lactic acid) in skin regeneration. Accordingly, this review addresses the fundamental concept of cell–matrix communication, which helps us to understand the basis of the polymer’s functions in the biomedical field. |
| first_indexed | 2024-03-10T22:36:38Z |
| format | Article |
| id | doaj.art-dc7234db66e54253ac9fb28f620b4a54 |
| institution | Directory Open Access Journal |
| issn | 2504-477X |
| language | English |
| last_indexed | 2024-03-10T22:36:38Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Composites Science |
| spelling | doaj.art-dc7234db66e54253ac9fb28f620b4a542023-11-19T11:22:40ZengMDPI AGJournal of Composites Science2504-477X2023-09-017938510.3390/jcs7090385Natural vs Synthetic Polymers: How Do They Communicate with Cells for Skin Regeneration—A ReviewJeevithan Elango0Camilo Zamora-Ledezma1José Eduardo Maté-Sánchez de Val2Department of Biomaterials Engineering, Faculty of Health Sciences, UCAM-Universidad Católica San Antonio de Murcia, Guadalupe, 30107 Murcia, SpainGreen and Innovative Technologies for Food, Environment and Bioengineering Research Group, Faculty of Pharmacy and Nutrition, UCAM-Universidad Católica San Antonio de Murcia, 30107 Murcia, SpainDepartment of Biomaterials Engineering, Faculty of Health Sciences, UCAM-Universidad Católica San Antonio de Murcia, Guadalupe, 30107 Murcia, SpainModern research has evolved several approaches toward skin regeneration and one of the novel concerns is the use of polymer-based systems due to their excellent beneficial properties to the skin. Several polymers, such as cellulose, hyaluronan, alginate, chitosan, collagen, fibrin and fibroin, have been tested and have proven the benefits for skin regeneration, and most of them are derived from either polysaccharide- or protein-based materials. In order to understand the mode of action, several researchers investigated the cell–matrix interaction and possible signaling mechanism in skin regeneration. Not only the signaling mechanism but also the mode of cell communication determines the application of polysaccharide- and protein-based polymers in practice. Based on the above significance, this review disclosed the recent findings to compile a possible method of communication between cells and polymers derived from polysaccharide-based (such as cellulose, hyaluronan, chitosan, alginate, agar, and xanthan gum) and protein-based (such as collagen, gelatin, fibrin, and silk fibroin) materials along with other polymers, such as poly(vinyl alcohol), polyglycolide or poly(glycolic acid), or poly(lactic acid) in skin regeneration. Accordingly, this review addresses the fundamental concept of cell–matrix communication, which helps us to understand the basis of the polymer’s functions in the biomedical field.https://www.mdpi.com/2504-477X/7/9/385natural polymerssynthetic polymersskin regenerationfibroblastscell–matrix communication |
| spellingShingle | Jeevithan Elango Camilo Zamora-Ledezma José Eduardo Maté-Sánchez de Val Natural vs Synthetic Polymers: How Do They Communicate with Cells for Skin Regeneration—A Review Journal of Composites Science natural polymers synthetic polymers skin regeneration fibroblasts cell–matrix communication |
| title | Natural vs Synthetic Polymers: How Do They Communicate with Cells for Skin Regeneration—A Review |
| title_full | Natural vs Synthetic Polymers: How Do They Communicate with Cells for Skin Regeneration—A Review |
| title_fullStr | Natural vs Synthetic Polymers: How Do They Communicate with Cells for Skin Regeneration—A Review |
| title_full_unstemmed | Natural vs Synthetic Polymers: How Do They Communicate with Cells for Skin Regeneration—A Review |
| title_short | Natural vs Synthetic Polymers: How Do They Communicate with Cells for Skin Regeneration—A Review |
| title_sort | natural vs synthetic polymers how do they communicate with cells for skin regeneration a review |
| topic | natural polymers synthetic polymers skin regeneration fibroblasts cell–matrix communication |
| url | https://www.mdpi.com/2504-477X/7/9/385 |
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