Escherichia coli BarA-UvrY regulates the pks island and kills Staphylococci via the genotoxin colibactin during interspecies competition.

Escherichia coli BarA-UvrY regulates the pks island and kills Staphylococci via the genotoxin colibactin during interspecies competition.

Wound infections are often polymicrobial in nature, biofilm associated and therefore tolerant to antibiotic therapy, and associated with delayed healing. Escherichia coli and Staphylococcus aureus are among the most frequently cultured pathogens from wound infections. However, little is known about...

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Bibliographic Details
Main Authors: Jun Jie Wong, Foo Kiong Ho, Pei Yi Choo, Kelvin K L Chong, Chee Meng Benjamin Ho, Ramesh Neelakandan, Damien Keogh, Timothy Barkham, John Chen, Chuan Fa Liu, Kimberly A Kline
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010766

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