Cloning, characterization, and heterologous expression of a candidate Hirudin gene from the salivary gland transcriptome of Hirudo nipponia
Abstract Hirudin is a pharmacologically active substance in leeches with potent blood anticoagulation properties. Although recombinant hirudin production isolated from Hirudo medicinalis Linnaeus and Hirudinaria manillensis Lesson is known, to our knowledge, this study is the first to report recombi...
Main Authors: | Ping Shi, Jian Wei, Huajian You, Shijiang Chen, Fayin Tan, Zenghui Lu |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-32303-2 |
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