Deficits in arithmetic error detection in infants with prenatal alcohol exposure: An ERP study
Prenatal alcohol exposure (PAE) is associated with a range of physical, cognitive, and behavioral problems, particularly in arithmetic. We report ERP data collected from 32 infants (mean age = 6.8 mo; SD = 0.6; range = 6.1–8.1; 16 typically developing [TD]; 16 prenatally alcohol-exposed) during a ta...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-12-01
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| Series: | Developmental Cognitive Neuroscience |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878929319303093 |
| _version_ | 1830514760042414080 |
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| author | Andrea Berger Michael Shmueli Svetlana Lisson Mattan S. Ben-Shachar Nadine M. Lindinger Catherine E. Lewis Neil C. Dodge Christopher D. Molteno Ernesta M. Meintjes Joseph L. Jacobson Sandra W. Jacobson |
| author_facet | Andrea Berger Michael Shmueli Svetlana Lisson Mattan S. Ben-Shachar Nadine M. Lindinger Catherine E. Lewis Neil C. Dodge Christopher D. Molteno Ernesta M. Meintjes Joseph L. Jacobson Sandra W. Jacobson |
| author_sort | Andrea Berger |
| collection | DOAJ |
| description | Prenatal alcohol exposure (PAE) is associated with a range of physical, cognitive, and behavioral problems, particularly in arithmetic. We report ERP data collected from 32 infants (mean age = 6.8 mo; SD = 0.6; range = 6.1–8.1; 16 typically developing [TD]; 16 prenatally alcohol-exposed) during a task designed to assess error detection. Evidence of error monitoring at this early age suggests that precursors of the onset of executive control can already be detected in infancy. As predicted, the ERPs of the TD infants, time-locked to the presentation of the solution to simple arithmetic equations, showed greater negative activity for the incorrect solution condition at middle-frontal scalp areas. Spectral analysis indicated specificity to the 6–7 Hz frequency range. By contrast, the alcohol-exposed infants did not show the increased middle-frontal negativity seen in the TD group nor the increased power in the 6–7 Hz frequency, suggesting a marked developmental delay in error detection and/or early impairment in information processing of small quantities. Overall, our research demonstrates that (a) the brain network involved in error detection can be identified and highly specified in TD young infants, and (b) this effect is replicable and can be utilized for studying developmental psychopathology at very early ages. Keywords: EEG phase synchronization, Prenatal alcohol exposure, Fetal alcohol spectrum disorders, Error detection, Theta, Infants |
| first_indexed | 2024-12-22T03:09:06Z |
| format | Article |
| id | doaj.art-dc778df1634249f9b9a7028aea45de2a |
| institution | Directory Open Access Journal |
| issn | 1878-9293 |
| language | English |
| last_indexed | 2024-12-22T03:09:06Z |
| publishDate | 2019-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Developmental Cognitive Neuroscience |
| spelling | doaj.art-dc778df1634249f9b9a7028aea45de2a2022-12-21T18:40:58ZengElsevierDevelopmental Cognitive Neuroscience1878-92932019-12-0140Deficits in arithmetic error detection in infants with prenatal alcohol exposure: An ERP studyAndrea Berger0Michael Shmueli1Svetlana Lisson2Mattan S. Ben-Shachar3Nadine M. Lindinger4Catherine E. Lewis5Neil C. Dodge6Christopher D. Molteno7Ernesta M. Meintjes8Joseph L. Jacobson9Sandra W. Jacobson10Department of Psychology and Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer Sheva, Israel; Corresponding author at: Department of Psychology, Ben-Gurion University of the Negev, Beer Sheva, 84105, IsraelDepartment of Psychology and Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer Sheva, IsraelDepartment of Psychology and Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer Sheva, IsraelDepartment of Psychology and Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer Sheva, IsraelDepartment of Human Biology, University of Cape Town, Faculty of Health Sciences, Cape Town, South AfricaDepartment of Human Biology, University of Cape Town, Faculty of Health Sciences, Cape Town, South AfricaDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, United StatesDepartment of Psychiatry and Mental Health, University of Cape Town, Faculty of Health Sciences, Cape Town, South AfricaDepartment of Human Biology, University of Cape Town, Faculty of Health Sciences, Cape Town, South Africa; MRC/UCT Medical Imaging Research Unit, University of Cape Town, Division of Biomedical Engineering, Faculty of Health Sciences, Cape Town, South AfricaDepartment of Human Biology, University of Cape Town, Faculty of Health Sciences, Cape Town, South Africa; Department of Psychiatry and Mental Health, University of Cape Town, Faculty of Health Sciences, Cape Town, South AfricaDepartment of Human Biology, University of Cape Town, Faculty of Health Sciences, Cape Town, South Africa; Department of Psychiatry and Mental Health, University of Cape Town, Faculty of Health Sciences, Cape Town, South AfricaPrenatal alcohol exposure (PAE) is associated with a range of physical, cognitive, and behavioral problems, particularly in arithmetic. We report ERP data collected from 32 infants (mean age = 6.8 mo; SD = 0.6; range = 6.1–8.1; 16 typically developing [TD]; 16 prenatally alcohol-exposed) during a task designed to assess error detection. Evidence of error monitoring at this early age suggests that precursors of the onset of executive control can already be detected in infancy. As predicted, the ERPs of the TD infants, time-locked to the presentation of the solution to simple arithmetic equations, showed greater negative activity for the incorrect solution condition at middle-frontal scalp areas. Spectral analysis indicated specificity to the 6–7 Hz frequency range. By contrast, the alcohol-exposed infants did not show the increased middle-frontal negativity seen in the TD group nor the increased power in the 6–7 Hz frequency, suggesting a marked developmental delay in error detection and/or early impairment in information processing of small quantities. Overall, our research demonstrates that (a) the brain network involved in error detection can be identified and highly specified in TD young infants, and (b) this effect is replicable and can be utilized for studying developmental psychopathology at very early ages. Keywords: EEG phase synchronization, Prenatal alcohol exposure, Fetal alcohol spectrum disorders, Error detection, Theta, Infantshttp://www.sciencedirect.com/science/article/pii/S1878929319303093 |
| spellingShingle | Andrea Berger Michael Shmueli Svetlana Lisson Mattan S. Ben-Shachar Nadine M. Lindinger Catherine E. Lewis Neil C. Dodge Christopher D. Molteno Ernesta M. Meintjes Joseph L. Jacobson Sandra W. Jacobson Deficits in arithmetic error detection in infants with prenatal alcohol exposure: An ERP study Developmental Cognitive Neuroscience |
| title | Deficits in arithmetic error detection in infants with prenatal alcohol exposure: An ERP study |
| title_full | Deficits in arithmetic error detection in infants with prenatal alcohol exposure: An ERP study |
| title_fullStr | Deficits in arithmetic error detection in infants with prenatal alcohol exposure: An ERP study |
| title_full_unstemmed | Deficits in arithmetic error detection in infants with prenatal alcohol exposure: An ERP study |
| title_short | Deficits in arithmetic error detection in infants with prenatal alcohol exposure: An ERP study |
| title_sort | deficits in arithmetic error detection in infants with prenatal alcohol exposure an erp study |
| url | http://www.sciencedirect.com/science/article/pii/S1878929319303093 |
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