Ventilator-associated pneumonia (VAP) and pleural empyema caused by multidrug-resistant Acinetobacter baumannii in HIV and COVID 19 infected patient: A case report

Ventilator-associated pneumonia (VAP) and pleural empyema caused by multidrug-resistant Acinetobacter baumannii in HIV and COVID 19 infected patient: A case report

Summary: We analyzed the case of a 49-year-old woman with HIV infection off-therapy with poor viro-immunological compensation, not vaccinated for SARS-COV-2, hospitalized for lobar pneumonia and severe COVID19-related respiratory failure in intensive care unit (ICU). The hospitalization was complica...

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Bibliographic Details
Main Authors: Rosa Anna Passerotto, Francesco Lamanna, Damiano Farinacci, Alex Dusina, Simona Di Giambenedetto, Arturo Ciccullo, Alberto Borghetti
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Infectious Medicine
Subjects:
Acinetobacter baumannii
colistin
cefiderocol
SARS-CoV-2
HIV
Online Access:http://www.sciencedirect.com/science/article/pii/S2772431X23000096
Description
Summary:Summary: We analyzed the case of a 49-year-old woman with HIV infection off-therapy with poor viro-immunological compensation, not vaccinated for SARS-COV-2, hospitalized for lobar pneumonia and severe COVID19-related respiratory failure in intensive care unit (ICU). The hospitalization was complicated by bacteraemic ventilator-associated pneumonia (VAP) caused by multidrug-resistant Acinetobacter baumannii (MDR-AB) isolated on pleural fluid culture, treated with colistin and cefiderocol for about 3 weeks. The molecular research of MDR-AB on transtracheal aspirate was negative following this therapy.The aim is to show the safety, efficacy and tolerability of colistin-based combination therapy with cefiderocol for Acinetobacter baumannii infection in HIV-infected patient.
ISSN:2772-431X

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