Loss of cortical control over the descending pain modulatory system determines the development of the neuropathic pain state in rats

The loss of descending inhibitory control is thought critical to the development of chronic pain but what causes this loss in function is not well understood. We have investigated the dynamic contribution of prelimbic cortical neuronal projections to the periaqueductal grey (PrL-P) to the developmen...

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Bibliografische gegevens
Hoofdauteurs: Robert AR Drake, Kenneth A Steel, Richard Apps, Bridget M Lumb, Anthony E Pickering
Formaat: Artikel
Taal:English
Gepubliceerd in: eLife Sciences Publications Ltd 2021-02-01
Reeks:eLife
Onderwerpen:
Online toegang:https://elifesciences.org/articles/65156