Synthesis and Olfactory Evaluation of Bulky Moiety-Modified Analogues to the Sandalwood Odorant Polysantol®
Five new bulky moiety-modified analogues of the sandalwood odorant Polysantol® have been synthesized by aldol condensation of appropriate aldehydes with butanone, deconjugative α-methylation of the resulting α,β-unsaturated ketones, and reduction of the corresponding β,γ-unsaturated ketones. The fin...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2009-07-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/14/8/2780/ |
| _version_ | 1818751788183977984 |
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| author | Adolfo Sánchez Manuel Nogueras Sofía Salido Concepción Badía Joaquín Altarejos Pablo J. Linares-Palomino Laura Chapado |
| author_facet | Adolfo Sánchez Manuel Nogueras Sofía Salido Concepción Badía Joaquín Altarejos Pablo J. Linares-Palomino Laura Chapado |
| author_sort | Adolfo Sánchez |
| collection | DOAJ |
| description | Five new bulky moiety-modified analogues of the sandalwood odorant Polysantol® have been synthesized by aldol condensation of appropriate aldehydes with butanone, deconjugative α-methylation of the resulting α,β-unsaturated ketones, and reduction of the corresponding β,γ-unsaturated ketones. The final compounds were evaluated organoleptically and one of them seemed to be of special interest for its natural sandalwood scent. |
| first_indexed | 2024-12-18T04:41:08Z |
| format | Article |
| id | doaj.art-dc7a2ea0a0824cb3bf37aceb3d9facd6 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-18T04:41:08Z |
| publishDate | 2009-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-dc7a2ea0a0824cb3bf37aceb3d9facd62022-12-21T21:20:43ZengMDPI AGMolecules1420-30492009-07-011482780280010.3390/molecules14082780Synthesis and Olfactory Evaluation of Bulky Moiety-Modified Analogues to the Sandalwood Odorant Polysantol®Adolfo SánchezManuel NoguerasSofía SalidoConcepción BadíaJoaquín AltarejosPablo J. Linares-PalominoLaura ChapadoFive new bulky moiety-modified analogues of the sandalwood odorant Polysantol® have been synthesized by aldol condensation of appropriate aldehydes with butanone, deconjugative α-methylation of the resulting α,β-unsaturated ketones, and reduction of the corresponding β,γ-unsaturated ketones. The final compounds were evaluated organoleptically and one of them seemed to be of special interest for its natural sandalwood scent.http://www.mdpi.com/1420-3049/14/8/2780/sandalwood odorantsPolysantol® analoguesnopol derivativeodour evaluation |
| spellingShingle | Adolfo Sánchez Manuel Nogueras Sofía Salido Concepción Badía Joaquín Altarejos Pablo J. Linares-Palomino Laura Chapado Synthesis and Olfactory Evaluation of Bulky Moiety-Modified Analogues to the Sandalwood Odorant Polysantol® Molecules sandalwood odorants Polysantol® analogues nopol derivative odour evaluation |
| title | Synthesis and Olfactory Evaluation of Bulky Moiety-Modified Analogues to the Sandalwood Odorant Polysantol® |
| title_full | Synthesis and Olfactory Evaluation of Bulky Moiety-Modified Analogues to the Sandalwood Odorant Polysantol® |
| title_fullStr | Synthesis and Olfactory Evaluation of Bulky Moiety-Modified Analogues to the Sandalwood Odorant Polysantol® |
| title_full_unstemmed | Synthesis and Olfactory Evaluation of Bulky Moiety-Modified Analogues to the Sandalwood Odorant Polysantol® |
| title_short | Synthesis and Olfactory Evaluation of Bulky Moiety-Modified Analogues to the Sandalwood Odorant Polysantol® |
| title_sort | synthesis and olfactory evaluation of bulky moiety modified analogues to the sandalwood odorant polysantol r |
| topic | sandalwood odorants Polysantol® analogues nopol derivative odour evaluation |
| url | http://www.mdpi.com/1420-3049/14/8/2780/ |
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