Acetaminophen overdose followed by ingestion of an herbicide: A case of unique combination

Drug overdose and herbicide consumption are two common methods that are widely used for self-destruction. This article presents a unique case of self-poisoning by ingestion of Acetaminophen (Paracetamol) followed by herbicide 2-Methyl-4-chlorophenoxyacetic Acid (MCPA). No such a case has been report...

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Main Authors: Amal Nishantha Vadysinghe, Herath Mudiyanselage Yudhayangani Yureka Bandara, Solokara Mudiyanselage Nirmani Kaushalya Thilakarathne, Liyanage Madhuka Malshani Liyanage
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Forensic Science International: Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2665910719300313
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author Amal Nishantha Vadysinghe
Herath Mudiyanselage Yudhayangani Yureka Bandara
Solokara Mudiyanselage Nirmani Kaushalya Thilakarathne
Liyanage Madhuka Malshani Liyanage
author_facet Amal Nishantha Vadysinghe
Herath Mudiyanselage Yudhayangani Yureka Bandara
Solokara Mudiyanselage Nirmani Kaushalya Thilakarathne
Liyanage Madhuka Malshani Liyanage
author_sort Amal Nishantha Vadysinghe
collection DOAJ
description Drug overdose and herbicide consumption are two common methods that are widely used for self-destruction. This article presents a unique case of self-poisoning by ingestion of Acetaminophen (Paracetamol) followed by herbicide 2-Methyl-4-chlorophenoxyacetic Acid (MCPA). No such a case has been reported in the literature. A 53-year-old male was admitted vomiting and semi-conscious, with a history of ingestion of MCPA. He was treated with gastric lavage, activated charcoal, sodium bicarbonate, intravenous fluids and, antibiotics. He succumbed despite mechanical ventilation. Death investigation revealed fatal toxicity with MCPA and acetaminophen with the possible manner of death being stated as complex suicide. This case highlights the importance of considering the ingestion of a second poison by clinicians and forensic pathologists when response to the appropriate management of a specific poison is poor. Keywords: Acetaminophen, Drug overdose, MCPA, Paracetamol, Suicide
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spelling doaj.art-dc7a3567b34b43bcbac40892647034bf2022-12-21T18:11:22ZengElsevierForensic Science International: Reports2665-91072019-11-011Acetaminophen overdose followed by ingestion of an herbicide: A case of unique combinationAmal Nishantha Vadysinghe0Herath Mudiyanselage Yudhayangani Yureka Bandara1Solokara Mudiyanselage Nirmani Kaushalya Thilakarathne2Liyanage Madhuka Malshani Liyanage3Corresponding author.; Department of Forensic Medicine, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri LankaDepartment of Forensic Medicine, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri LankaDepartment of Forensic Medicine, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri LankaDepartment of Forensic Medicine, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri LankaDrug overdose and herbicide consumption are two common methods that are widely used for self-destruction. This article presents a unique case of self-poisoning by ingestion of Acetaminophen (Paracetamol) followed by herbicide 2-Methyl-4-chlorophenoxyacetic Acid (MCPA). No such a case has been reported in the literature. A 53-year-old male was admitted vomiting and semi-conscious, with a history of ingestion of MCPA. He was treated with gastric lavage, activated charcoal, sodium bicarbonate, intravenous fluids and, antibiotics. He succumbed despite mechanical ventilation. Death investigation revealed fatal toxicity with MCPA and acetaminophen with the possible manner of death being stated as complex suicide. This case highlights the importance of considering the ingestion of a second poison by clinicians and forensic pathologists when response to the appropriate management of a specific poison is poor. Keywords: Acetaminophen, Drug overdose, MCPA, Paracetamol, Suicidehttp://www.sciencedirect.com/science/article/pii/S2665910719300313
spellingShingle Amal Nishantha Vadysinghe
Herath Mudiyanselage Yudhayangani Yureka Bandara
Solokara Mudiyanselage Nirmani Kaushalya Thilakarathne
Liyanage Madhuka Malshani Liyanage
Acetaminophen overdose followed by ingestion of an herbicide: A case of unique combination
Forensic Science International: Reports
title Acetaminophen overdose followed by ingestion of an herbicide: A case of unique combination
title_full Acetaminophen overdose followed by ingestion of an herbicide: A case of unique combination
title_fullStr Acetaminophen overdose followed by ingestion of an herbicide: A case of unique combination
title_full_unstemmed Acetaminophen overdose followed by ingestion of an herbicide: A case of unique combination
title_short Acetaminophen overdose followed by ingestion of an herbicide: A case of unique combination
title_sort acetaminophen overdose followed by ingestion of an herbicide a case of unique combination
url http://www.sciencedirect.com/science/article/pii/S2665910719300313
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AT solokaramudiyanselagenirmanikaushalyathilakarathne acetaminophenoverdosefollowedbyingestionofanherbicideacaseofuniquecombination
AT liyanagemadhukamalshaniliyanage acetaminophenoverdosefollowedbyingestionofanherbicideacaseofuniquecombination