The bZIP Ap1 transcription factor is a negative regulator of virulence attributes of the anthropophilic dermatophyte Trichophyton rubrum

The bZIP Ap1 transcription factor is a negative regulator of virulence attributes of the anthropophilic dermatophyte Trichophyton rubrum

Trichophyton rubrum is a fungus that causes chronic skin and nail infections in healthy individuals and immunocompromised patients. During infection, T. rubrum invades host cutaneous tissues by adapting to the acidic pH and the innate immune response of the host. Several genes are upregulated during...

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Bibliographic Details
Main Authors: Nalu T.A. Peres, Elza A.S. Lang, Tamires A. Bitencourt, Vanderci M. Oliveira, Ana Lucia Fachin, Antonio Rossi, Nilce M. Martinez-Rossi
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Microbial Sciences
Subjects:
Trichophyton rubrum
ap1 gene
Nail infection
Gene deletion
Fungal-host interaction
Chronicity of onychomycosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2666517422000293

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