A gene based combination test using GWAS summary data

Abstract Background Gene-based association tests provide a useful alternative and complement to the usual single marker association tests, especially in genome-wide association studies (GWAS). The way of weighting for variants in a gene plays an important role in boosting the power of a gene-based a...

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Autori principali: Jianjun Zhang, Xiaoyu Liang, Samantha Gonzales, Jianguo Liu, Xiaoyi Raymond Gao, Xuexia Wang
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2023-01-01
Serie:BMC Bioinformatics
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Accesso online:https://doi.org/10.1186/s12859-022-05114-x