New Retinal Pigment Epithelial Cell Model to Unravel Neuroprotection Sensors of Neurodegeneration in Retinal Disease

New Retinal Pigment Epithelial Cell Model to Unravel Neuroprotection Sensors of Neurodegeneration in Retinal Disease

Retinal pigment epithelial (RPE) cells sustain photoreceptor integrity, and when this function is disrupted, retinal degenerations ensue. Herein, we characterize a new cell line from human RPE that we termed ABC. These cells remarkably recapitulate human eye native cells. Distinctive from other epit...

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Bibliographic Details
Main Authors: Aram Asatryan, Jorgelina M. Calandria, Marie-Audrey I. Kautzmann, Bokkyoo Jun, William C. Gordon, Khanh V. Do, Surjyadipta Bhattacharjee, Thang L. Pham, Vicente Bermúdez, Melina Valeria Mateos, Jessica Heap, Nicolas G. Bazan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Neuroscience
Subjects:
neuroprotectin D1
RPE cell
single cell
gene expression
lipids
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.926629/full

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