Circular RNA circ-CPA4/ let-7 miRNA/PD-L1 axis regulates cell growth, stemness, drug resistance and immune evasion in non-small cell lung cancer (NSCLC)

Circular RNA circ-CPA4/ let-7 miRNA/PD-L1 axis regulates cell growth, stemness, drug resistance and immune evasion in non-small cell lung cancer (NSCLC)

Abstract Background Non-small cell lung cancer (NSCLC) cells derived intracellular and extracellular programmed cell death ligand 1 (PD-L1) promoted cancer progression and drug resistance, and facilitated tumor immune evasion. However, the detailed molecular mechanisms are still largely unknown. In...

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Bibliographic Details
Main Authors: Weijun Hong, Min Xue, Jun Jiang, Yajuan Zhang, Xiwen Gao
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
NSCLC
Immune evasion
Stemness
PD-L1
Circ-CPA4
Let-7 miRNA
Online Access:http://link.springer.com/article/10.1186/s13046-020-01648-1

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