The effect of quercetin supplementation on the components of metabolic syndrome in adults: A systematic review and dose–response meta-analysis of randomized controlled trials
This systematic review and meta-analysis of randomized controlled trials (RCTs) sought to evaluate the effects of quercetin on the components of (MetS) such as waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), triglyceride (TG), and...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464624001774 |
| _version_ | 1797210063444639744 |
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| author | Nooshin Noshadi Atefeh Bonyadian Ali Hojati Mahdieh Abbasalizad-Farhangi Marzieh Heidari Melika Darzi Hooria Seyedhosseini-Ghaheh Mahsa khajeh Fatemeh Pourteymour Fard Tabrizi Mahdi Vajdi Gholamreza Askari |
| author_facet | Nooshin Noshadi Atefeh Bonyadian Ali Hojati Mahdieh Abbasalizad-Farhangi Marzieh Heidari Melika Darzi Hooria Seyedhosseini-Ghaheh Mahsa khajeh Fatemeh Pourteymour Fard Tabrizi Mahdi Vajdi Gholamreza Askari |
| author_sort | Nooshin Noshadi |
| collection | DOAJ |
| description | This systematic review and meta-analysis of randomized controlled trials (RCTs) sought to evaluate the effects of quercetin on the components of (MetS) such as waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), triglyceride (TG), and high-density lipoprotein cholesterol (HDL-C). A systematic literature search up to December 2023 was completed in Scopus, PubMed, Embase, and Web of Science, to identify eligible RCTs. Altogether, 20 studies with a total sample size of 1,164 subjects were included in the analysis. A pooled analysis showed that quercetin consumption led to a significant reduction in FBG (WMD: −1.03 mg/dL; 95 % CI: −1.87 to −0.19), and SBP (WMD: −1.96 mmHg; 95 % CI: −3.11 to −0.81). However, there were no significant effects on TG, HDL-C, WC, and DBP. It was found that quercetin intake can decrease FBG and SBP significantly without significant effects on other components of MetS. |
| first_indexed | 2024-04-24T10:04:38Z |
| format | Article |
| id | doaj.art-dc88f8b092854ae5820d6e64ea745f4f |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-04-24T10:04:38Z |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-dc88f8b092854ae5820d6e64ea745f4f2024-04-13T04:21:05ZengElsevierJournal of Functional Foods1756-46462024-05-01116106175The effect of quercetin supplementation on the components of metabolic syndrome in adults: A systematic review and dose–response meta-analysis of randomized controlled trialsNooshin Noshadi0Atefeh Bonyadian1Ali Hojati2Mahdieh Abbasalizad-Farhangi3Marzieh Heidari4Melika Darzi5Hooria Seyedhosseini-Ghaheh6Mahsa khajeh7Fatemeh Pourteymour Fard Tabrizi8Mahdi Vajdi9Gholamreza Askari10Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, IranNutrition Research Center, Department of Clinical Nutrition, Faculty of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Community Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Community Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, IranNutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, IranStudent Research Committee, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Community Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran; Corresponding authors at: Student Research Committee, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran (M. Vajdi); Department of Community Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran (F. Pourteymour Fard Tabrizi).Student Research Committee, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran; Corresponding authors at: Student Research Committee, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran (M. Vajdi); Department of Community Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran (F. Pourteymour Fard Tabrizi).Department of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, IranThis systematic review and meta-analysis of randomized controlled trials (RCTs) sought to evaluate the effects of quercetin on the components of (MetS) such as waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), triglyceride (TG), and high-density lipoprotein cholesterol (HDL-C). A systematic literature search up to December 2023 was completed in Scopus, PubMed, Embase, and Web of Science, to identify eligible RCTs. Altogether, 20 studies with a total sample size of 1,164 subjects were included in the analysis. A pooled analysis showed that quercetin consumption led to a significant reduction in FBG (WMD: −1.03 mg/dL; 95 % CI: −1.87 to −0.19), and SBP (WMD: −1.96 mmHg; 95 % CI: −3.11 to −0.81). However, there were no significant effects on TG, HDL-C, WC, and DBP. It was found that quercetin intake can decrease FBG and SBP significantly without significant effects on other components of MetS.http://www.sciencedirect.com/science/article/pii/S1756464624001774QuercetinMetabolic syndromeObesityMeta‐analysis |
| spellingShingle | Nooshin Noshadi Atefeh Bonyadian Ali Hojati Mahdieh Abbasalizad-Farhangi Marzieh Heidari Melika Darzi Hooria Seyedhosseini-Ghaheh Mahsa khajeh Fatemeh Pourteymour Fard Tabrizi Mahdi Vajdi Gholamreza Askari The effect of quercetin supplementation on the components of metabolic syndrome in adults: A systematic review and dose–response meta-analysis of randomized controlled trials Journal of Functional Foods Quercetin Metabolic syndrome Obesity Meta‐analysis |
| title | The effect of quercetin supplementation on the components of metabolic syndrome in adults: A systematic review and dose–response meta-analysis of randomized controlled trials |
| title_full | The effect of quercetin supplementation on the components of metabolic syndrome in adults: A systematic review and dose–response meta-analysis of randomized controlled trials |
| title_fullStr | The effect of quercetin supplementation on the components of metabolic syndrome in adults: A systematic review and dose–response meta-analysis of randomized controlled trials |
| title_full_unstemmed | The effect of quercetin supplementation on the components of metabolic syndrome in adults: A systematic review and dose–response meta-analysis of randomized controlled trials |
| title_short | The effect of quercetin supplementation on the components of metabolic syndrome in adults: A systematic review and dose–response meta-analysis of randomized controlled trials |
| title_sort | effect of quercetin supplementation on the components of metabolic syndrome in adults a systematic review and dose response meta analysis of randomized controlled trials |
| topic | Quercetin Metabolic syndrome Obesity Meta‐analysis |
| url | http://www.sciencedirect.com/science/article/pii/S1756464624001774 |
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