Nanomaterials as Non-viral siRNA Delivery Agents for Cancer Therapy
Gene therapy has been recently shown as a promising tool for cancer treatment as nanotechnology-based safe and effective delivery methods are developed. Generally, genes are wrapped up in extremely tiny nanoparticles which could be taken up easily by cancer cells, not to their healthy neighboring ce...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2013-01-01
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| Series: | BioImpacts |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.5681/bi.2013.007 |
| _version_ | 1811337418710712320 |
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| author | Sanjay Singh |
| author_facet | Sanjay Singh |
| author_sort | Sanjay Singh |
| collection | DOAJ |
| description | Gene therapy has been recently shown as a promising tool for cancer treatment as nanotechnology-based safe and effective delivery methods are developed. Generally, genes are wrapped up in extremely tiny nanoparticles which could be taken up easily by cancer cells, not to their healthy neighboring cells. Several nanoparticle systems have been investigated primarily to address the problems involved in other methods of gene delivery and observed improved anticancer efficacy suggesting that nanomedicine provides novel opportunities to safely deliver genes, thus treat cancer. In this review, various nanoparticle types and related strategies, used in gene delivery for cancer treatment, have been discussed. |
| first_indexed | 2024-04-13T17:54:37Z |
| format | Article |
| id | doaj.art-dc8e37830d75414796210eb92d3c8057 |
| institution | Directory Open Access Journal |
| issn | 2228-5652 2228-5660 |
| language | English |
| last_indexed | 2024-04-13T17:54:37Z |
| publishDate | 2013-01-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | BioImpacts |
| spelling | doaj.art-dc8e37830d75414796210eb92d3c80572022-12-22T02:36:34ZengTabriz University of Medical SciencesBioImpacts2228-56522228-56602013-01-0132536510.5681/bi.2013.007Nanomaterials as Non-viral siRNA Delivery Agents for Cancer TherapySanjay SinghGene therapy has been recently shown as a promising tool for cancer treatment as nanotechnology-based safe and effective delivery methods are developed. Generally, genes are wrapped up in extremely tiny nanoparticles which could be taken up easily by cancer cells, not to their healthy neighboring cells. Several nanoparticle systems have been investigated primarily to address the problems involved in other methods of gene delivery and observed improved anticancer efficacy suggesting that nanomedicine provides novel opportunities to safely deliver genes, thus treat cancer. In this review, various nanoparticle types and related strategies, used in gene delivery for cancer treatment, have been discussed.http://dx.doi.org/10.5681/bi.2013.007Cancer TherapyCancer NanotechnologyNanomedicinesNanomaterialsGene Delivery |
| spellingShingle | Sanjay Singh Nanomaterials as Non-viral siRNA Delivery Agents for Cancer Therapy BioImpacts Cancer Therapy Cancer Nanotechnology Nanomedicines Nanomaterials Gene Delivery |
| title | Nanomaterials as Non-viral siRNA Delivery Agents for Cancer Therapy |
| title_full | Nanomaterials as Non-viral siRNA Delivery Agents for Cancer Therapy |
| title_fullStr | Nanomaterials as Non-viral siRNA Delivery Agents for Cancer Therapy |
| title_full_unstemmed | Nanomaterials as Non-viral siRNA Delivery Agents for Cancer Therapy |
| title_short | Nanomaterials as Non-viral siRNA Delivery Agents for Cancer Therapy |
| title_sort | nanomaterials as non viral sirna delivery agents for cancer therapy |
| topic | Cancer Therapy Cancer Nanotechnology Nanomedicines Nanomaterials Gene Delivery |
| url | http://dx.doi.org/10.5681/bi.2013.007 |
| work_keys_str_mv | AT sanjaysingh nanomaterialsasnonviralsirnadeliveryagentsforcancertherapy |