Integrated serum, urine metabolomics and 16S rRNA sequencing to investigate the modulatory effect of Ziziphi Spinosae Folium flavonoid on D-galactose-induced aging of rats

Integrated serum, urine metabolomics and 16S rRNA sequencing to investigate the modulatory effect of Ziziphi Spinosae Folium flavonoid on D-galactose-induced aging of rats

Ziziphi Spinosae Folium, the leaf of Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou (LZJS), was widely distributed in northern China. Our previous study showed that LZJS flavonoid (LZJSF) exerted antioxidant activity at chemical and PC12 cell levels, respectively. Here, we further studi...

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Bibliographic Details
Main Authors: Yu Tao, Cai Fu, Huizhi Du, Chenhui Du, Yan Yan
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Arabian Journal of Chemistry
Subjects:
Ziziphi Spinosae Folium flavonoids
Anti-aging
Cognitive dysfunction
Metabolomics
16S rRNA sequencing
“microbiota-gut-brain” axis
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223010535

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http://www.sciencedirect.com/science/article/pii/S1878535223010535

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