Neutrophilic inflammation promotes SARS-CoV-2 infectivity and augments the inflammatory responses in airway epithelial cells

Neutrophilic inflammation promotes SARS-CoV-2 infectivity and augments the inflammatory responses in airway epithelial cells

IntroductionIn response to viral infection, neutrophils release inflammatory mediators as part of the innate immune response, contributing to pathogen clearance through virus internalization and killing. Pre- existing co-morbidities correlating to incidence to severe COVID-19 are associated with chr...

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Bibliographic Details
Main Authors: Ben A. Calvert, Erik J. Quiroz, Zareeb Lorenzana, Ngan Doan, Seongjae Kim, Christiana N. Senger, Jeffrey J. Anders, Wiliam D. Wallace, Matthew P. Salomon, Jill Henley, Amy L. Ryan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
airway epithelium
cell-cell interactions
cytokines
inflammation
neutrophils
viral infection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1112870/full

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