Seminal transferrin in the seminal quality evaluation of hemodialytic patients
Objective: to verify the association between seminal quality and seminal transferrin (ST) level and fertility index in patients undergoing chronic hemodialysis (CH). Material and methods: This is a cross-sectional study in a group of 60 men (case) undergoing CH for more than 6 months, and a group o...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2018-03-01
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| Series: | Archivio Italiano di Urologia e Andrologia |
| Subjects: | |
| Online Access: | http://www.pagepressjournals.org/index.php/aiua/article/view/7282 |
| _version_ | 1818448734924570624 |
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| author | Gilmar Pereira Silva Fabiana Pirani Carneiro Vitor Pereira Xavier Grangeiro |
| author_facet | Gilmar Pereira Silva Fabiana Pirani Carneiro Vitor Pereira Xavier Grangeiro |
| author_sort | Gilmar Pereira Silva |
| collection | DOAJ |
| description | Objective: to verify the association between seminal quality and seminal transferrin (ST) level and fertility index in patients undergoing chronic hemodialysis (CH).
Material and methods: This is a cross-sectional study in a group of 60 men (case) undergoing CH for more than 6 months, and a group of 30 healthy men (control), aged 18-60 years, without clinical or laboratory signs of infection/inflammation. Spermiogram was performed, fertility index (FI) was calculated and ST and sex hormones (SH) levels were measured, including follicle-stimulating hormone, luteinizing hormone, total testosterone, and prolactin.
Results: All individuals were eugonadal. No differences for age (49.47 ± 5.56, 47.90 ± 6.2, p = 0.22) were observed between cases and controls, whereas there were significant differences between the individuals in the case and control groups with respect to the mean FI (p = 0.000), seminal parameters (SP) (p = 0.000), and ST levels (40.12 ± 08.25 vs 73.32 ± 06.8, p = 0.000). ST levels were correlated with FI (r = 0.787, p = 0.00) and SP (motility: r = 0.857, p = 0.000; vitality: r = 0.551, p = 0.000; density: r = 0.850, p = 0.000; normal morphology: r = 0.386, p = 0.000). Linear regression model showed relationship of ST levels with total sperm motility (R2 = 0.701; p = 0.000) and and FI (R2 = 0.569; p = 0.000).
Conclusions: Our results suggest that seminal quality is associated with ST levels and FI and that it can be used the initial investigation of subfertility/infertility of patients undergoing chronic hemodialysis.. |
| first_indexed | 2024-12-14T20:24:14Z |
| format | Article |
| id | doaj.art-dc908322317a4d7ebe6a54f7941ab6bc |
| institution | Directory Open Access Journal |
| issn | 1124-3562 2282-4197 |
| language | English |
| last_indexed | 2024-12-14T20:24:14Z |
| publishDate | 2018-03-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Archivio Italiano di Urologia e Andrologia |
| spelling | doaj.art-dc908322317a4d7ebe6a54f7941ab6bc2022-12-21T22:48:40ZengPAGEPress PublicationsArchivio Italiano di Urologia e Andrologia1124-35622282-41972018-03-01901495310.4081/aiua.2018.1.495645Seminal transferrin in the seminal quality evaluation of hemodialytic patientsGilmar Pereira Silva0Fabiana Pirani Carneiro1Vitor Pereira Xavier Grangeiro2University of Brasilia, Brasilia, Federal DistrictUniversity of Brasilia, Brasilia, Federal DistrictFaculty of Medical Sciences, João Pessoa, ParaibaObjective: to verify the association between seminal quality and seminal transferrin (ST) level and fertility index in patients undergoing chronic hemodialysis (CH). Material and methods: This is a cross-sectional study in a group of 60 men (case) undergoing CH for more than 6 months, and a group of 30 healthy men (control), aged 18-60 years, without clinical or laboratory signs of infection/inflammation. Spermiogram was performed, fertility index (FI) was calculated and ST and sex hormones (SH) levels were measured, including follicle-stimulating hormone, luteinizing hormone, total testosterone, and prolactin. Results: All individuals were eugonadal. No differences for age (49.47 ± 5.56, 47.90 ± 6.2, p = 0.22) were observed between cases and controls, whereas there were significant differences between the individuals in the case and control groups with respect to the mean FI (p = 0.000), seminal parameters (SP) (p = 0.000), and ST levels (40.12 ± 08.25 vs 73.32 ± 06.8, p = 0.000). ST levels were correlated with FI (r = 0.787, p = 0.00) and SP (motility: r = 0.857, p = 0.000; vitality: r = 0.551, p = 0.000; density: r = 0.850, p = 0.000; normal morphology: r = 0.386, p = 0.000). Linear regression model showed relationship of ST levels with total sperm motility (R2 = 0.701; p = 0.000) and and FI (R2 = 0.569; p = 0.000). Conclusions: Our results suggest that seminal quality is associated with ST levels and FI and that it can be used the initial investigation of subfertility/infertility of patients undergoing chronic hemodialysis..http://www.pagepressjournals.org/index.php/aiua/article/view/7282Chronic kidney diseaseHemodialysisMale infertilitySeminal transferrinSeminal qualitySeminal parameters |
| spellingShingle | Gilmar Pereira Silva Fabiana Pirani Carneiro Vitor Pereira Xavier Grangeiro Seminal transferrin in the seminal quality evaluation of hemodialytic patients Archivio Italiano di Urologia e Andrologia Chronic kidney disease Hemodialysis Male infertility Seminal transferrin Seminal quality Seminal parameters |
| title | Seminal transferrin in the seminal quality evaluation of hemodialytic patients |
| title_full | Seminal transferrin in the seminal quality evaluation of hemodialytic patients |
| title_fullStr | Seminal transferrin in the seminal quality evaluation of hemodialytic patients |
| title_full_unstemmed | Seminal transferrin in the seminal quality evaluation of hemodialytic patients |
| title_short | Seminal transferrin in the seminal quality evaluation of hemodialytic patients |
| title_sort | seminal transferrin in the seminal quality evaluation of hemodialytic patients |
| topic | Chronic kidney disease Hemodialysis Male infertility Seminal transferrin Seminal quality Seminal parameters |
| url | http://www.pagepressjournals.org/index.php/aiua/article/view/7282 |
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