The Pathophysiologic Role of Gelsolin in Chronic Kidney Disease: Focus on Podocytes

The Pathophysiologic Role of Gelsolin in Chronic Kidney Disease: Focus on Podocytes

Chronic kidney disease (CKD) is normally related to proteinuria, a common finding in a compromised glomerular filtration barrier (GFB). GFB is a structure composed of glomerular endothelial cells, the basement membrane, and the podocytes. CKD with podocyte damage may be associated with actin cytoske...

Full description

Bibliographic Details
Main Authors:	Chia-Jung Yu, Dian W. Damaiyanti, Shian-Jang Yan, Chih-Hsing Wu, Ming-Jer Tang, Dar-Bin Shieh, Peter P. Liu, Ping-Yen Liu
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Series:	International Journal of Molecular Sciences
Subjects:	podocyte gelsolin actin chronic kidney disease
Online Access:	https://www.mdpi.com/1422-0067/22/24/13281

Similar Items

The expanding superfamily of gelsolin homology domain proteins
by: Ghoshdastider, Umesh, et al.
Published: (2016)

Plasma Gelsolin: Indicator of Inflammation and Its Potential as a Diagnostic Tool and Therapeutic Target
by: Ewelina Piktel, et al.
Published: (2018-08-01)

Gelsolin Attenuates Neonatal Hyperoxia-Induced Inflammatory Responses to Rhinovirus Infection and Preserves Alveolarization
by: Tracy X. Cui, et al.
Published: (2022-01-01)

CHANGE IN BLOOD GELSOLIN CONCENTRATION IN RESPONSE TO PHYSICAL EXERCISE
by: Jan Górski, et al.
Published: (2013-06-01)

Implication of plasma gelsolin in systemic lupus erythematosus patients
by: Ghada M. Mosaad, et al.
Published: (2022-01-01)

Altered Expression Ratio of Actin-Binding Gelsolin Isoforms Is a Novel Hallmark of Mitochondrial OXPHOS Dysfunction
by: Alberto García-Bartolomé, et al.
Published: (2020-08-01)

PODOCYTES… WHATS UNDER YOURS? (PODOCYTES AND FOOT PROCESSES AND HOW THEY CHANGE IN NEPHROPATHY)
by: Chris Robert Neal
Published: (2015-02-01)

Gelsolin Inhibits the Inflammatory Process Induced by LPS
by: Ying Cheng, et al.
Published: (2017-01-01)

Gelsolin of insect vectors negatively regulates actin-based tubule motility of plant reoviruses
by: Qian Chen, et al.
Published: (2019-05-01)

Presepsin: gelsolin ratio, as a promising marker of sepsis-related organ dysfunction: a prospective observational study
by: Dániel Ragán, et al.
Published: (2023-05-01)

Gelsolin as a Potential Clinical Biomarker in Psoriasis Vulgaris
by: Sul Hee Lee, et al.
Published: (2023-02-01)

Coupled Electrostatic and Hydrophobic Destabilisation of the Gelsolin-Actin Complex Enables Facile Detection of Ovarian Cancer Biomarker Lysophosphatidic Acid
by: Katharina Davoudian, et al.
Published: (2023-09-01)

Interleukin-18 and Gelsolin Are Associated with Acute Kidney Disease after Cardiac Catheterization
by: Po-Yen Kuo, et al.
Published: (2023-03-01)

Gelsolin as a Potential Biomarker for Endoscopic Activity and Mucosal Healing in Ulcerative Colitis
by: Keiko Maeda, et al.
Published: (2022-04-01)

Gelsolin Can Be a Prognostic Biomarker and Correlated with Immune Infiltrates in Gastric Cancer
by: Wu Y, et al.
Published: (2022-01-01)

Evaluation of the Relationship Between Expression of Villin and Gelsolin Genes and Axillary Lymph Node Metastasis in Patients with Breast Cancer
by: Armin Borhan, et al.
Published: (2021-01-01)

Emerging roles of plasma gelsolin in tumorigenesis and modulating the tumor microenvironment
by: Chih‐Hsiung Hsieh, et al.
Published: (2022-09-01)

Physical Interaction between HPV16E7 and the Actin-Binding Protein Gelsolin Regulates Epithelial-Mesenchymal Transition via HIPPO-YAP Axis
by: Paola Matarrese, et al.
Published: (2021-01-01)

Regulation of the Actin Cytoskeleton in Podocytes
by: Judith Blaine, et al.
Published: (2020-07-01)

Podocytes: recent biomolecular developments
by: Armelloni Silvia, et al.
Published: (2014-08-01)

Rational Design of a Peptidomimetic Inhibitor of Gelsolin Amyloid Aggregation
by: Michela Bollati, et al.
Published: (2022-11-01)

Recombinant human gelsolin promotes the migration of human articular cartilage chondrocytes by regulating gene expression in vitro
by: Jessica Feldt, et al.
Published: (2020-12-01)

Podocentric view of glomerular proteinuria: Focused on cytoskeletal changes and toward promising targeted therapies and challenges
by: Mei‐Chuan Kuo, et al.
Published: (2021-07-01)

Production and Secretion of Gelsolin by Both Human Macrophage- and Fibroblast-like Synoviocytes and GSN Modulation in the Synovial Fluid of Patients with Various Forms of Arthritis
by: Jessica Feldt, et al.
Published: (2022-03-01)

Levamisole Modulation of Podocytes’ Actin Cytoskeleton in Nephrotic Syndrome
by: Susan T. Veissi, et al.
Published: (2023-11-01)

Evaluation of plasma hepcidin, cystatin-C and gelsolin in ovine theileriosis (Ghezel breed) based on age and parasitemia rate
by: Kaveh Azimzadeh, et al.
Published: (2017-04-01)

Drug Release from Gelsolin-Targeted Phase-Transition Nanoparticles Triggered by Low-Intensity Focused Ultrasound
by: Qin H, et al.
Published: (2022-01-01)

Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury
by: Sheng Zhi-Yong, et al.
Published: (2011-09-01)

The Lipid-Binding Defective Dynamin 2 Mutant in Charcot-Marie-Tooth Disease Impairs Proper Actin Bundling and Actin Organization in Glomerular Podocytes
by: Eriko Hamasaki, et al.
Published: (2022-05-01)

Reorganization of the actin cytoskeleton during the formation of neutrophil extracellular traps (NETs)
by: Hans Georg Mannherz, et al.
Published: (2024-06-01)

Role of Plasma Gelsolin Protein in the Final Stage of Erythropoiesis and in Correction of Erythroid Dysplasia In Vitro
by: So Yeon Han, et al.
Published: (2020-09-01)

Circulating Plasma Gelsolin: A Predictor of Favorable Clinical Outcomes in Head and Neck Cancer and Sensitive Biomarker for Early Disease Diagnosis Combined with Soluble Fas Ligand
by: Chen-Tzu Chiu, et al.
Published: (2020-06-01)

Gelsolin expression in sheep milk somatic cells during lactation
by: F. Napolitano, et al.
Published: (2019-01-01)

The targeting imaging and treatment capacity of gelsolin-targeted and paclitaxel-loaded PLGA nanoparticles in vitro and in vivo
by: Jiamei Ji, et al.
Published: (2022-10-01)

NeuroD Expression in Podocytes and Interrelationships with Nephrin at Both Nuclear and Cytoplasmic Sites
by: Silvia Armelloni, et al.
Published: (2018-04-01)

Caspase Cleavage of Gelsolin Is an Inductive Cue for Pathologic Cardiac Hypertrophy
by: Charis Putinski, et al.
Published: (2018-12-01)

Hearing problems in patients with hereditary gelsolin amyloidosis
by: Tuuli Mustonen, et al.
Published: (2021-10-01)

Regulation of Mitochondrial Function by the Actin Cytoskeleton
by: María Illescas, et al.
Published: (2021-12-01)

Detection of the Ovarian Cancer Biomarker Lysophosphatidic Acid in Serum
by: Brian De La Franier, et al.
Published: (2020-02-01)

Podocyte Pathology and Nephropathy
by: Sandra eMerscher, et al.
Published: (2014-07-01)