Force-induced Caspase-1-dependent pyroptosis regulates orthodontic tooth movement

Abstract Pyroptosis, an inflammatory caspase-dependent programmed cell death, plays a vital role in maintaining tissue homeostasis and activating inflammatory responses. Orthodontic tooth movement (OTM) is an aseptic force-induced inflammatory bone remodeling process mediated by the activation of pe...

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Bibliographic Details
Main Authors: Liyuan Chen, Huajie Yu, Zixin Li, Yu Wang, Shanshan Jin, Min Yu, Lisha Zhu, Chengye Ding, Xiaolan Wu, Tianhao Wu, Chunlei Xun, Yanheng Zhou, Danqing He, Yan Liu
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-023-00268-7