Siglec-1 Expressed on Dendritic Cells is a New Receptor Implicated in Arenavirus Uptake

Siglec-1 Expressed on Dendritic Cells is a New Receptor Implicated in Arenavirus Uptake

Arenaviruses are enveloped viruses that cause hemorrhagic fever outbreaks in humans and still lack an effective antiviral treatment. Upon early infection, these viruses target dendritic cells (DCs), which can promote systemic viral dissemination, contributing to pathogenesis. We have previously desc...

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Bibliographic Details
Main Authors: Xabier Muniz-Trabudua, Cristina Borio, Marcos Bilen, Itziar Erkizia, Daniel Perez-Zsolt, Susana Benet, Javier Martinez-Picado, Nuria Izquierdo-Useros
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Proceedings
Subjects:
arenavirus
dendritic cells
Siglec-1
Online Access:https://www.mdpi.com/2504-3900/50/1/90

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