Diffusion fMRI detects white-matter dysfunction in mice with acute optic neuritis

Diffusion fMRI detects white-matter dysfunction in mice with acute optic neuritis

Optic neuritis is a frequent and early symptom of multiple sclerosis (MS). Conventional magnetic resonance (MR) techniques provide means to assess multiple MS-related pathologies, including axonal injury, demyelination, and inflammation. A method to directly and non-invasively probe white-matter fun...

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Bibliographic Details
Main Authors: Tsen-Hsuan Lin, William M. Spees, Chia-Wen Chiang, Kathryn Trinkaus, Anne H. Cross, Sheng-Kwei Song
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Neurobiology of Disease
Subjects:
Diffusion fMRI
White matter
EAE
Optic neuritis
Visual acuity
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114000497

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