Gitelman′s syndrome with panhypopituitarism: Reno-endocrine interplay
Gitelman′s syndrome is an inherited tubulopathy affecting thiazide-sensitive sodium chloride cotransporter, which manifests with hypokalemic alkalosis, hypomagnesemia, and hypocalciuria. Recently few cases have been described having an association of Gitelman′s syndrome with pituitary abnormalities...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2012-01-01
|
| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=2;spage=297;epage=299;aulast=Upreti |
| _version_ | 1811202495957958656 |
|---|---|
| author | Vimal Upreti Chetan Sharda B. V. N Kumar Pawan Dhull M S Prakash |
| author_facet | Vimal Upreti Chetan Sharda B. V. N Kumar Pawan Dhull M S Prakash |
| author_sort | Vimal Upreti |
| collection | DOAJ |
| description | Gitelman′s syndrome is an inherited tubulopathy affecting thiazide-sensitive sodium chloride cotransporter, which manifests with hypokalemic alkalosis, hypomagnesemia, and hypocalciuria. Recently few cases have been described having an association of Gitelman′s syndrome with pituitary abnormalities on imaging, though with normal hormonal status. We describe the first case of an adult patient having Gitelman′s syndrome and hypopituitarism with abnormal pituitary imaging. She presented to us with hypotension, hypokalemia, hypomagnesemia with alkalosis, hypothyroidism, hypocortisolism, and hypogonadism. She was treated with replacement of electrolytes and hormones, to which she showed an excellent response. |
| first_indexed | 2024-04-12T02:40:18Z |
| format | Article |
| id | doaj.art-dca2ee270bcf4704b745162f5ea9efe0 |
| institution | Directory Open Access Journal |
| issn | 2230-8210 2230-9500 |
| language | English |
| last_indexed | 2024-04-12T02:40:18Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-dca2ee270bcf4704b745162f5ea9efe02022-12-22T03:51:20ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002012-01-0116229729910.4103/2230-8210.93774Gitelman′s syndrome with panhypopituitarism: Reno-endocrine interplayVimal UpretiChetan ShardaB. V. N KumarPawan DhullM S PrakashGitelman′s syndrome is an inherited tubulopathy affecting thiazide-sensitive sodium chloride cotransporter, which manifests with hypokalemic alkalosis, hypomagnesemia, and hypocalciuria. Recently few cases have been described having an association of Gitelman′s syndrome with pituitary abnormalities on imaging, though with normal hormonal status. We describe the first case of an adult patient having Gitelman′s syndrome and hypopituitarism with abnormal pituitary imaging. She presented to us with hypotension, hypokalemia, hypomagnesemia with alkalosis, hypothyroidism, hypocortisolism, and hypogonadism. She was treated with replacement of electrolytes and hormones, to which she showed an excellent response.http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=2;spage=297;epage=299;aulast=UpretiGitelman′s syndromehypokalemiahypomagnesemiainherited tubulopathymultiple pituitary hormone deficiencies |
| spellingShingle | Vimal Upreti Chetan Sharda B. V. N Kumar Pawan Dhull M S Prakash Gitelman′s syndrome with panhypopituitarism: Reno-endocrine interplay Indian Journal of Endocrinology and Metabolism Gitelman′s syndrome hypokalemia hypomagnesemia inherited tubulopathy multiple pituitary hormone deficiencies |
| title | Gitelman′s syndrome with panhypopituitarism: Reno-endocrine interplay |
| title_full | Gitelman′s syndrome with panhypopituitarism: Reno-endocrine interplay |
| title_fullStr | Gitelman′s syndrome with panhypopituitarism: Reno-endocrine interplay |
| title_full_unstemmed | Gitelman′s syndrome with panhypopituitarism: Reno-endocrine interplay |
| title_short | Gitelman′s syndrome with panhypopituitarism: Reno-endocrine interplay |
| title_sort | gitelman s syndrome with panhypopituitarism reno endocrine interplay |
| topic | Gitelman′s syndrome hypokalemia hypomagnesemia inherited tubulopathy multiple pituitary hormone deficiencies |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=2;spage=297;epage=299;aulast=Upreti |
| work_keys_str_mv | AT vimalupreti gitelmanssyndromewithpanhypopituitarismrenoendocrineinterplay AT chetansharda gitelmanssyndromewithpanhypopituitarismrenoendocrineinterplay AT bvnkumar gitelmanssyndromewithpanhypopituitarismrenoendocrineinterplay AT pawandhull gitelmanssyndromewithpanhypopituitarismrenoendocrineinterplay AT msprakash gitelmanssyndromewithpanhypopituitarismrenoendocrineinterplay |