Aplasia eritroide aguda y amegacariocitosis por el lupus eritematoso sistémico
Background - Anemia and thrombocytopenia are common features in patients with systemic lupus erythematosus (SLE). However, erythroid aplasia and amegakaryocytosis as the main physiopathological causes without other associated disorders have been rarely described. Case report – We report of a 29...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Galega de Medicina Interna
2023-09-01
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| Series: | Galicia Clínica |
| Subjects: | |
| Online Access: | https://galiciaclinica.info/publicacion.asp?f=2910 |
| _version_ | 1797688706773024768 |
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| author | Rui Suzano Juvenal Morais José Fernandes Judite Sachicumbi Luis Caminal-Montero |
| author_facet | Rui Suzano Juvenal Morais José Fernandes Judite Sachicumbi Luis Caminal-Montero |
| author_sort | Rui Suzano |
| collection | DOAJ |
| description | Background -
Anemia and thrombocytopenia are common features in patients with systemic lupus erythematosus (SLE). However, erythroid aplasia and amegakaryocytosis as the main physiopathological causes without other associated disorders have been rarely described.
Case report –
We report of a 29 y/o female with diagnosis of SLE presenting with severe anemia and thrombocytopenia due to a bone marrow immunological blockage. Patient, who initially refused transfusions, was successfully treated and had a very fast hematological response to steroids, immunoglobulin, plasma exchange, eltrombopag and rituximab.
Discussion–
This is an unusual case and it is possible that in this kind of patients plasma exchange associated with immunosuppressant therapy may lead to a faster, more effective and sustained recovery of the hematological disorders. |
| first_indexed | 2024-03-12T01:34:36Z |
| format | Article |
| id | doaj.art-dca360c41a924a9ea6bd7d5b2e5c9eec |
| institution | Directory Open Access Journal |
| issn | 0304-4866 1989-3922 |
| language | English |
| last_indexed | 2024-03-12T01:34:36Z |
| publishDate | 2023-09-01 |
| publisher | Sociedade Galega de Medicina Interna |
| record_format | Article |
| series | Galicia Clínica |
| spelling | doaj.art-dca360c41a924a9ea6bd7d5b2e5c9eec2023-09-11T11:20:15ZengSociedade Galega de Medicina InternaGalicia Clínica0304-48661989-39222023-09-01842384010.22546/69/29102910Aplasia eritroide aguda y amegacariocitosis por el lupus eritematoso sistémicoRui Suzano0Juvenal Morais1José Fernandes2Judite Sachicumbi3Luis Caminal-Montero4Dept Internal Medicine/Systemic Autoimune Diseases Unit. Hospital da HortaDepartment of Intensive Care Medicine, Hospital da HortaDepartment of Hematology, Hospital da HortaDepartament of Pathology, Hospital da HortaInternal Medicine, Hospital Universitario Central de AsturiasBackground - Anemia and thrombocytopenia are common features in patients with systemic lupus erythematosus (SLE). However, erythroid aplasia and amegakaryocytosis as the main physiopathological causes without other associated disorders have been rarely described. Case report – We report of a 29 y/o female with diagnosis of SLE presenting with severe anemia and thrombocytopenia due to a bone marrow immunological blockage. Patient, who initially refused transfusions, was successfully treated and had a very fast hematological response to steroids, immunoglobulin, plasma exchange, eltrombopag and rituximab. Discussion– This is an unusual case and it is possible that in this kind of patients plasma exchange associated with immunosuppressant therapy may lead to a faster, more effective and sustained recovery of the hematological disorders.https://galiciaclinica.info/publicacion.asp?f=2910lupus eritematoso sistémicoaplasia eritroideamegacariocitosisplasmaféresistratamientos inmunosupresores |
| spellingShingle | Rui Suzano Juvenal Morais José Fernandes Judite Sachicumbi Luis Caminal-Montero Aplasia eritroide aguda y amegacariocitosis por el lupus eritematoso sistémico Galicia Clínica lupus eritematoso sistémico aplasia eritroide amegacariocitosis plasmaféresis tratamientos inmunosupresores |
| title | Aplasia eritroide aguda y amegacariocitosis por el lupus eritematoso sistémico |
| title_full | Aplasia eritroide aguda y amegacariocitosis por el lupus eritematoso sistémico |
| title_fullStr | Aplasia eritroide aguda y amegacariocitosis por el lupus eritematoso sistémico |
| title_full_unstemmed | Aplasia eritroide aguda y amegacariocitosis por el lupus eritematoso sistémico |
| title_short | Aplasia eritroide aguda y amegacariocitosis por el lupus eritematoso sistémico |
| title_sort | aplasia eritroide aguda y amegacariocitosis por el lupus eritematoso sistemico |
| topic | lupus eritematoso sistémico aplasia eritroide amegacariocitosis plasmaféresis tratamientos inmunosupresores |
| url | https://galiciaclinica.info/publicacion.asp?f=2910 |
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