The gut efflux pump MRP-1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learning
The multidrug resistance-associated protein-1 (MRP-1) functions in the basolateral membrane of intestinal cells to transport byproducts of cellular redox reactions to control both molecular and behavioral immunity in C. elegans.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-05-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03381-1 |
| _version_ | 1811304813880672256 |
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| author | Jonathan Lalsiamthara Alejandro Aballay |
| author_facet | Jonathan Lalsiamthara Alejandro Aballay |
| author_sort | Jonathan Lalsiamthara |
| collection | DOAJ |
| description | The multidrug resistance-associated protein-1 (MRP-1) functions in the basolateral membrane of intestinal cells to transport byproducts of cellular redox reactions to control both molecular and behavioral immunity in C. elegans. |
| first_indexed | 2024-04-13T08:14:03Z |
| format | Article |
| id | doaj.art-dca760673a6c41cf9ec196c49eb5d4fc |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-13T08:14:03Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-dca760673a6c41cf9ec196c49eb5d4fc2022-12-22T02:54:52ZengNature PortfolioCommunications Biology2399-36422022-05-015111310.1038/s42003-022-03381-1The gut efflux pump MRP-1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learningJonathan Lalsiamthara0Alejandro Aballay1Department of Molecular Microbiology and Immunology, School of Medicine, Oregon Health & Science University PortlandDepartment of Molecular Microbiology and Immunology, School of Medicine, Oregon Health & Science University PortlandThe multidrug resistance-associated protein-1 (MRP-1) functions in the basolateral membrane of intestinal cells to transport byproducts of cellular redox reactions to control both molecular and behavioral immunity in C. elegans.https://doi.org/10.1038/s42003-022-03381-1 |
| spellingShingle | Jonathan Lalsiamthara Alejandro Aballay The gut efflux pump MRP-1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learning Communications Biology |
| title | The gut efflux pump MRP-1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learning |
| title_full | The gut efflux pump MRP-1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learning |
| title_fullStr | The gut efflux pump MRP-1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learning |
| title_full_unstemmed | The gut efflux pump MRP-1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learning |
| title_short | The gut efflux pump MRP-1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learning |
| title_sort | gut efflux pump mrp 1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learning |
| url | https://doi.org/10.1038/s42003-022-03381-1 |
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