Circulating tumour cell gene expression and chemosensitivity analyses: predictive accuracy for response to multidisciplinary treatment of patients with unresectable refractory recurrent rectal cancer or unresectable refractory colorectal cancer liver metastases

Circulating tumour cell gene expression and chemosensitivity analyses: predictive accuracy for response to multidisciplinary treatment of patients with unresectable refractory recurrent rectal cancer or unresectable refractory colorectal cancer liver metastases

Abstract Background Patients with unresectable recurrent rectal cancer (RRC) or colorectal cancer (CRC) with liver metastases, refractory to at least two lines of traditional systemic therapy, may receive third line intraarterial chemotherapy (IC) and targeted therapy (TT) using drugs selected by ch...

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Bibliographic Details
Main Authors: Stefano Guadagni, Francesco Masedu, Giammaria Fiorentini, Donatella Sarti, Caterina Fiorentini, Veronica Guadagni, Panagiotis Apostolou, Ioannis Papasotiriou, Panagiotis Parsonidis, Marco Valenti, Enrico Ricevuto, Gemma Bruera, Antonietta R. Farina, Andrew R. Mackay, Marco Clementi
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Cancer
Subjects:
Predictive accuracy
Precision oncotherapy
Liquid biopsies
Circulating tumor cells
Chemosensitivity tests
Tumor gene expressions analyses
Online Access:https://doi.org/10.1186/s12885-022-09770-3

Internet

https://doi.org/10.1186/s12885-022-09770-3

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