Pyridine and p-Nitrophenyl Oxime Esters with Possible Photochemotherapeutic Activity: Synthesis, DNA Photocleavage and DNA Binding Studies

Pyridine and p-Nitrophenyl Oxime Esters with Possible Photochemotherapeutic Activity: Synthesis, DNA Photocleavage and DNA Binding Studies

Compared to standard treatments for various diseases, photochemotherapy and photo-dynamic therapy are less invasive approaches, in which DNA photocleavers represent promising tools for novel “on demand” chemotherapeutics. A series of p-nitrobenzoyl and p-pyridoyl ester conjugated aldoximes, amidoxim...

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Bibliographic Details
Main Authors:	Milena Pasolli, Konstantinos Dafnopoulos, Nicolaos-Panagiotis Andreou, Panagiotis S. Gritzapis, Maria Koffa, Alexandros E. Koumbis, George Psomas, Konstantina C. Fylaktakidou
Format:	Article
Language:	English
Published:	MDPI AG 2016-06-01
Series:	Molecules
Subjects:	photo-cleavage DNA photo-cleavers DNA binding oxime esters amidoxime aldoxime ketoxime
Online Access:	http://www.mdpi.com/1420-3049/21/7/864

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