Multiple concomitant life-threatening opportunistic infections due to uncontrolled hypercortisolism
Opportunistic infections associated with severe cortisol excess carry a high mortality rate and are most prevalent with ectopic ACTH syndrome. There are limited reports of these cases described in the literature. In this case report, we describe multiple severe life-threatening opportunistic infecti...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | IDCases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250922000488 |
| _version_ | 1818289286170017792 |
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| author | Sarah Al Qassimi Ahmad Nusair Mohamad Mooty Adnan Ajmal Saaid Abdel-Ghani |
| author_facet | Sarah Al Qassimi Ahmad Nusair Mohamad Mooty Adnan Ajmal Saaid Abdel-Ghani |
| author_sort | Sarah Al Qassimi |
| collection | DOAJ |
| description | Opportunistic infections associated with severe cortisol excess carry a high mortality rate and are most prevalent with ectopic ACTH syndrome. There are limited reports of these cases described in the literature. In this case report, we describe multiple severe life-threatening opportunistic infections due to endogenous hypercortisolism. Our patient, against numerous expectations, survived multiple opportunistic infections including disseminated invasive aspergillosis, Cytomegalovirus endophthalmitis and Pneumocystis Jirovecii pneumonia, reinforcing the need for multidisciplinary care for patients presenting with complicated hypercortisolism. |
| first_indexed | 2024-12-13T02:09:51Z |
| format | Article |
| id | doaj.art-dcb1fea4ba63435281669342b3873f87 |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-12-13T02:09:51Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-dcb1fea4ba63435281669342b3873f872022-12-22T00:03:02ZengElsevierIDCases2214-25092022-01-0127e01420Multiple concomitant life-threatening opportunistic infections due to uncontrolled hypercortisolismSarah Al Qassimi0Ahmad Nusair1Mohamad Mooty2Adnan Ajmal3Saaid Abdel-Ghani4Medical Subspecialties Institute – Hospital Medicine, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; Corresponding author.Medical Subspecialties Institute – Infectious Diseases, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab EmiratesMedical Subspecialties Institute – Infectious Diseases, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab EmiratesMedical Subspecialties Institute – Endocrinology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab EmiratesMedical Subspecialties Institute – Hospital Medicine, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab EmiratesOpportunistic infections associated with severe cortisol excess carry a high mortality rate and are most prevalent with ectopic ACTH syndrome. There are limited reports of these cases described in the literature. In this case report, we describe multiple severe life-threatening opportunistic infections due to endogenous hypercortisolism. Our patient, against numerous expectations, survived multiple opportunistic infections including disseminated invasive aspergillosis, Cytomegalovirus endophthalmitis and Pneumocystis Jirovecii pneumonia, reinforcing the need for multidisciplinary care for patients presenting with complicated hypercortisolism.http://www.sciencedirect.com/science/article/pii/S2214250922000488Cushing’s syndromeHypercortisolismOpportunistic infectionsDisseminated aspergillosisCytomegalovirus endophthalmitisPneumocystis Jirovecii pneumonia |
| spellingShingle | Sarah Al Qassimi Ahmad Nusair Mohamad Mooty Adnan Ajmal Saaid Abdel-Ghani Multiple concomitant life-threatening opportunistic infections due to uncontrolled hypercortisolism IDCases Cushing’s syndrome Hypercortisolism Opportunistic infections Disseminated aspergillosis Cytomegalovirus endophthalmitis Pneumocystis Jirovecii pneumonia |
| title | Multiple concomitant life-threatening opportunistic infections due to uncontrolled hypercortisolism |
| title_full | Multiple concomitant life-threatening opportunistic infections due to uncontrolled hypercortisolism |
| title_fullStr | Multiple concomitant life-threatening opportunistic infections due to uncontrolled hypercortisolism |
| title_full_unstemmed | Multiple concomitant life-threatening opportunistic infections due to uncontrolled hypercortisolism |
| title_short | Multiple concomitant life-threatening opportunistic infections due to uncontrolled hypercortisolism |
| title_sort | multiple concomitant life threatening opportunistic infections due to uncontrolled hypercortisolism |
| topic | Cushing’s syndrome Hypercortisolism Opportunistic infections Disseminated aspergillosis Cytomegalovirus endophthalmitis Pneumocystis Jirovecii pneumonia |
| url | http://www.sciencedirect.com/science/article/pii/S2214250922000488 |
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