Identification of enhancers responsible for the coordinated expression of myosin heavy chain isoforms in skeletal muscle

Identification of enhancers responsible for the coordinated expression of myosin heavy chain isoforms in skeletal muscle

Abstract Background Skeletal muscles consist of fibers of differing contractility and metabolic properties, which are primarily determined by the content of myosin heavy chain (MYH) isoforms (MYH7, MYH2, MYH1, and MYH4). The regulation of Myh genes transcription depends on three-dimensional chromati...

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Bibliographic Details
Main Authors: Keren Long, Duo Su, Xiaokai Li, Hengkuan Li, Sha Zeng, Yu Zhang, Zhining Zhong, Yu Lin, Xuemin Li, Lu Lu, Long Jin, Jideng Ma, Qianzi Tang, Mingzhou Li
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Genomics
Subjects:
Myh genes
Chromatin interaction
4C-seq
Enhancer
Online Access:https://doi.org/10.1186/s12864-022-08737-9

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