EFFICACY OF TAMSULOSIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA IN TERMS OF TRIAL WITHOUT CATHETER, A RANDOMIZED CONTROL TRIAL
BACKGROUND & OBJECTIVE: Benign prostatic hyperplasia (BPH) is a prevalent cause of voiding problems in older males and is most commonly associated with acute urological complications, most important of which is acute urinary retention (AUR). α1- antagonists are the treatment of choice for the ma...
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| Format: | Article |
| Language: | English |
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University of Faisalabad
2021-08-01
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| Series: | Journal of University Medical & Dental College |
| Subjects: | |
| Online Access: | http://www.jumdc.com/index.php/jumdc/article/view/558 |
| _version_ | 1823989089889681408 |
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| author | Farhan Khan Usman Qamar Muhammad Saifullah Muhammad Sheraz Javed Ahsan Ali Arain Muhammad Sohail Murli Lal |
| author_facet | Farhan Khan Usman Qamar Muhammad Saifullah Muhammad Sheraz Javed Ahsan Ali Arain Muhammad Sohail Murli Lal |
| author_sort | Farhan Khan |
| collection | DOAJ |
| description | BACKGROUND & OBJECTIVE: Benign prostatic hyperplasia (BPH) is a prevalent cause of voiding problems in older males and is most commonly associated with acute urological complications, most important of which is acute urinary retention (AUR). α1- antagonists are the treatment of choice for the management of patients with BPH. Our objective was to evaluate the efficacy of tamsulosin for the treatment of patients with AUR due to BPH in terms of trial without catheter (TWOC).
METHODOLOGY: This randomized control trial was conducted in a Urology Section, Department of Surgery, SIUT Karachi, from 21-12-2016 to 20-06-2017. Our study included 136 patients who presented AUR due to BPH as per selection criteria. Patients were randomized into two groups. Group A patients received tamsulosin (0.4 mg), and group B patients received placebo drug immediately after insertion of Foley catheter. The success of TWOC was evaluated after 3 days of medical treatment. Statistical analysis was carried out using SPSS v20.0.
RESULTS: The mean age of the study patients was 59.45 + 8.05 years. The mean duration of BPH disease was 15.39 + 6.84 months. There were 33 (48.5%) patients in the tamsulosin group in which TWOC was successful and only 22 (32.4%) patients in placebo group in which TWOC was successful (p-value 0.04). There was no effect of age and duration of BPH disease on the outcome of this study.
CONCLUSION: Tamsulosin is effective for the treatment of patients with AUR due to BPH. |
| first_indexed | 2024-12-18T13:53:17Z |
| format | Article |
| id | doaj.art-dcb4362da64d42a48d6cf079ae75e34a |
| institution | Directory Open Access Journal |
| issn | 2221-7827 2310-5542 |
| language | English |
| last_indexed | 2024-12-18T13:53:17Z |
| publishDate | 2021-08-01 |
| publisher | University of Faisalabad |
| record_format | Article |
| series | Journal of University Medical & Dental College |
| spelling | doaj.art-dcb4362da64d42a48d6cf079ae75e34a2022-12-21T21:05:32ZengUniversity of FaisalabadJournal of University Medical & Dental College2221-78272310-55422021-08-0112310.37723/jumdc.v12i3.558EFFICACY OF TAMSULOSIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA IN TERMS OF TRIAL WITHOUT CATHETER, A RANDOMIZED CONTROL TRIALFarhan Khan0Usman Qamar1Muhammad Saifullah2Muhammad Sheraz Javed3Ahsan Ali Arain4Muhammad Sohail5Murli Lal6Lecturer, Department of Urology Sindh Institute of Urology and Transplantation, Karachi.Lecturer, Department of Urology Sindh Institute of Urology and Transplantation, Karachi.Senior Registrar, Department of Urology, District Head Quarter Hospital / Faisalabad Medical University.Senior Registrar, Department of Urology, District Head Quarter Hospital / Faisalabad Medical University.Registrar, Department of Urology, Liaquat University Hospital, Hyderabad / Jamshoro.Associate Professor, Department of Urology Aziz Fatima Medical and Dental College, Faisalabad.Professor Department of Urology, SIUT, Karachi.BACKGROUND & OBJECTIVE: Benign prostatic hyperplasia (BPH) is a prevalent cause of voiding problems in older males and is most commonly associated with acute urological complications, most important of which is acute urinary retention (AUR). α1- antagonists are the treatment of choice for the management of patients with BPH. Our objective was to evaluate the efficacy of tamsulosin for the treatment of patients with AUR due to BPH in terms of trial without catheter (TWOC). METHODOLOGY: This randomized control trial was conducted in a Urology Section, Department of Surgery, SIUT Karachi, from 21-12-2016 to 20-06-2017. Our study included 136 patients who presented AUR due to BPH as per selection criteria. Patients were randomized into two groups. Group A patients received tamsulosin (0.4 mg), and group B patients received placebo drug immediately after insertion of Foley catheter. The success of TWOC was evaluated after 3 days of medical treatment. Statistical analysis was carried out using SPSS v20.0. RESULTS: The mean age of the study patients was 59.45 + 8.05 years. The mean duration of BPH disease was 15.39 + 6.84 months. There were 33 (48.5%) patients in the tamsulosin group in which TWOC was successful and only 22 (32.4%) patients in placebo group in which TWOC was successful (p-value 0.04). There was no effect of age and duration of BPH disease on the outcome of this study. CONCLUSION: Tamsulosin is effective for the treatment of patients with AUR due to BPH.http://www.jumdc.com/index.php/jumdc/article/view/558TamsulosinBenign Prostatic HyperplasiaUrinary Retention |
| spellingShingle | Farhan Khan Usman Qamar Muhammad Saifullah Muhammad Sheraz Javed Ahsan Ali Arain Muhammad Sohail Murli Lal EFFICACY OF TAMSULOSIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA IN TERMS OF TRIAL WITHOUT CATHETER, A RANDOMIZED CONTROL TRIAL Journal of University Medical & Dental College Tamsulosin Benign Prostatic Hyperplasia Urinary Retention |
| title | EFFICACY OF TAMSULOSIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA IN TERMS OF TRIAL WITHOUT CATHETER, A RANDOMIZED CONTROL TRIAL |
| title_full | EFFICACY OF TAMSULOSIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA IN TERMS OF TRIAL WITHOUT CATHETER, A RANDOMIZED CONTROL TRIAL |
| title_fullStr | EFFICACY OF TAMSULOSIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA IN TERMS OF TRIAL WITHOUT CATHETER, A RANDOMIZED CONTROL TRIAL |
| title_full_unstemmed | EFFICACY OF TAMSULOSIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA IN TERMS OF TRIAL WITHOUT CATHETER, A RANDOMIZED CONTROL TRIAL |
| title_short | EFFICACY OF TAMSULOSIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA IN TERMS OF TRIAL WITHOUT CATHETER, A RANDOMIZED CONTROL TRIAL |
| title_sort | efficacy of tamsulosin in patients with benign prostatic hyperplasia in terms of trial without catheter a randomized control trial |
| topic | Tamsulosin Benign Prostatic Hyperplasia Urinary Retention |
| url | http://www.jumdc.com/index.php/jumdc/article/view/558 |
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