NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance
Summary: Oocyte maturation is vital to attain full competence required for fertilization and embryogenesis. NLRP14 is preferentially expressed in mammalian oocytes and early embryos. Yet, the role and molecular mechanism of NLRP14 in oocyte maturation and early embryogenesis are poorly understood, a...
Main Authors: | Wenzhe Zhang, Rongrong Zhang, Ling Wu, Chendi Zhu, Chuanxin Zhang, Chengpeng Xu, Shidou Zhao, Xinchen Liu, Ting Guo, Yueshuang Lu, Zheng Gao, Xiao Yu, Lei Li, Zi-Jiang Chen, Yingying Qin, Xue Jiao |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723015437 |
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