Calcium carbonates in gallstones
Relevance of the research. Сalcium carbonate, in the form of its three polymorphs: calcite, aragonite and vaterite, is included, beside natural systems, in composition of pathogenic biomineral aggregates, such as gallstones. The solution of the problem with calcium carbonate genesis in gallstones is...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Tomsk Polytechnic University
2019-05-01
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| Series: | Известия Томского политехнического университета: Инжиниринг георесурсов |
| Subjects: | |
| Online Access: | http://izvestiya.tpu.ru/archive/article/view/1511 |
| Summary: | Relevance of the research. Сalcium carbonate, in the form of its three polymorphs: calcite, aragonite and vaterite, is included, beside natural systems, in composition of pathogenic biomineral aggregates, such as gallstones. The solution of the problem with calcium carbonate genesis in gallstones is not only of medical practical value, but it also of a great interest from the point of view of mineralogical study. The study of morphological features, possible isomorphism, formation conditions of calcium carbonate in gallstones will allow comparing it with mineral analogues in natural objects, and thus, outlining the pattern of biomineral genesis. The aim of research is to study the distribution, the features of chemical composition and morphology of calcium carbonate in the gallstones of inhabitants of Komi Republic. Methods of research: X-Ray structural analysis (Shimadzu XRD-6000), electron microscope JSM 6400 with energy-dispersive spectrometer «Link». Results. The study of 50 gallstones samples by X-ray structural analysis showed that 39 samples contained calcium carbonate of various modifications. Vaterite was detected in 74 % of the analyzed carbonate-containing gallstones and in 38 % of samples vaterite was as the only polymorph. Simultaneously three polymorphs of calcium carbonate were determined only in 10 %. The REM study of morphological features of calcium carbonate showed that the carbonates were visualized as lamellar crystals, rhombohedrical, conical, dumpbell and irregular grains. The carbonates under study contain the admixtures: magnesium, manganese, iron and silicon, which content is less 2 wt. %. Conclusions. It was determined that vaterite is the dominant polymorph carbonate calcium in the studied gallstones. |
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| ISSN: | 2500-1019 2413-1830 |