Trilliumosides K and L, two novel steroidal saponins from rhizomes of Trillium govanianum, as potent anti-cancer agents targeting apoptosis in the A-549 cancer cell line

Trilliumosides K and L, two novel steroidal saponins from rhizomes of Trillium govanianum, as potent anti-cancer agents targeting apoptosis in the A-549 cancer cell line

Two novel steroidal saponins, trilliumosides K (1) and L (2), were isolated from the rhizomes of Trillium govanianum led by bioactivity-guided phytochemical investigation along with seven known compounds: govanoside D (3), protodioscin (4), borassoside E (5), 20-hydroxyecdysone (6), 5,20-hydroxyecdy...

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Bibliographic Details
Main Authors: Bashir Ahmad Lone, Misbah Tabassum, Anil Bhushan, Dixhya Rani, Urvashi Dhiman, Ajaz Ahmad, Hilal Ahmad Mir, Prem N. Gupta, D. M. Mondhe, Sumeet Gairola, Prasoon Gupta
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Chemistry
Subjects:
Trillium govanianum
saponins
steroidal glycosides
A-549
BAX
BCL-2
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1306271/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2023.1306271/full

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